Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | 97.0% | 751.42 | C38H59ClN4O7S | 1 G
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate designed as a building block for PROTAC synthesis and ligand-linker conjugate development in targeted protein degradation research. It contains an (S,R,S)-configured AHPC VHL ligand connected via a six-carbon PEG3 linker with a terminal chloro group to enable downstream conjugation.
- Useful as a VHL (E3 ligase) ligand building block for degrader design.
- C6-PEG3 linker provides flexibility and spacer length for bifunctional molecules.
- Terminal chloro group enables nucleophilic substitution or further functionalization.
- Characterized by analytical data including HPLC and LC-MS for batch confirmation.
- Provided as a solid suitable for synthetic chemistry workflows and storage under controlled conditions.
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Medchemexpress LLC Boc-NH-PEG3-propargyl | 1333880-60-6 | 97.0% | C14H25NO5 | 100 MG
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Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition with azide-containing molecules
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Medchemexpress LLC m-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 100 MG
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand for an E3 ubiquitin ligase
- The other ligand for the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 5 G
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Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules designed with two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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![Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202345.png-250.jpg)
Medchemexpress LLC Hydroxylamine, o-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 | C8H18N4O4 | 25 MG
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Aminooxy-PEG3-azide is a bifunctional PEG-based linker bearing an aminooxy group and an azide group, suitable for conjugation chemistry. It serves as a non-cleavable three-unit PEG spacer for synthesis of antibody-drug conjugates and PROTACs, and enables click chemistry reactions such as CuAAC and SPAAC.
- Used as a non-cleavable three-unit PEG linker for conjugation chemistry
- Contains aminooxy and azide functional groups for orthogonal conjugation
- Compatible with CuAAC and SPAAC click reactions
- Molecular weight 234.25 and formula C8H18N4O4
- Typical purity 95.0% (NMR)
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Medchemexpress LLC I-PEG5-OH 100mg
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 250 MG
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Tos-PEG5-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. It has a molecular weight of 476.58 and a chemical formula of C22H36O9S. Its appearance is a viscous liquid, colorless to light yellow.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Viscous liquid, colorless to light yellow appearance
- For research use only
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 99.2% | 810.01 g·mol⁻¹ | C42H59N5O9S | 10 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL E3 ligase ligand-linker conjugate used as a building block in the synthesis of PROTACs and other conjugates. It features a PEG3 spacer and a bicyclononyne (BCN) functional group to facilitate bioorthogonal conjugation and assembly of bifunctional molecules for targeted protein degradation research.
- VHL E3 ligase ligand for targeted protein degradation applications.
- PEG3 linker provides a flexible spacer for molecular conjugation.
- BCN functional group enables strain-promoted bioorthogonal click conjugation.
- Reported high purity suitable for synthetic chemistry use.
- Intended as a small-molecule building block for PROTAC assembly and conjugation workflows.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370807 TCO-PEG3-NH2 25MG
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eMolecules METHYLDIETHOXYSILANE 5G
5000188369 METHYLDIETHOXYSILANE 5G
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Medchemexpress LLC Biotin-PEG3-OH | 1263044-40-1 | 98.0% | 375.48 g·mol⁻¹ | C16H29N3O5S | 5 MG
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Biotin-PEG3-OH is a biotinylated polyethylene glycol (PEG3) linker designed for PROTAC synthesis and bioconjugation. It supplies a short, hydrophilic spacer with a terminal hydroxyl group and a biotin affinity handle for capture or detection in pull-down and labeling workflows.
- Biotin affinity tag for streptavidin-based capture and detection.
- PEG3 spacer provides hydrophilicity and flexible spacing.
- Terminal hydroxyl group enables further chemical modification.
- Available in small-scale quantities suitable for research workflows.
- Solid form with good solubility in DMSO for assay preparation.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000369394 TCO-PEG3-NH2 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000382150 BIS-PEG3-T-BUTYL EST 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000744879 POMALIDOMIDE-PEG3-AZ 100MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed AMBEED
5000867861 BIS-PEG5-ACID 1GR
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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