Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 25 G
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl-protected PEG3 (triethylene glycol) alcohol used as a synthetic building block for chemical synthesis, PEGylation, and drug-delivery research. It is supplied as a colorless to light yellow liquid with high purity and defined molecular properties.
- High purity suitable for research applications.
- Colorless to light yellow liquid, easy to handle in synthesis workflows.
- Defined molecular weight and formula for accurate formulation and calculations.
- Available in multiple pack sizes for flexible laboratory scale-up.
- Storage conditions support long-term stability in pure form and in solvent.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | ≥97.0% | 263.29 | C10H21N3O5 | 10 G
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Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker bearing a terminal azide and a terminal hydroxyl group. It functions as a non-cleavable, five-unit PEG spacer for bioconjugation and click chemistry applications.
- Contains azide (-N3) and terminal alcohol (-OH) functional groups.
- Water-soluble PEG linker suitable for click chemistry and PROTAC/ADC assembly.
- Molecular weight ~263.29 g/mol; formula C10H21N3O5.
- High purity, typically ≥97.0% by manufacturer specification.
- Available in multiple pack sizes, including 10 g.
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 100 MG
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Pomalidomide-PEG3-C2-NH2 hydrochloride is an E3 ligase ligand and linker conjugate. It is utilized in PROTAC technology for designing and developing novel targeted inhibitors. The E3 ligase ligand component, such as Pomalidomide, binds to a specific E3 ligase, while a linker connects it to a ligand that recognizes a targeted protein, a mechanism crucial for PROTAC activity.
- Functions as an E3 ligase ligand for Cereblon.
- Used in PROTAC technology.
- Aids in designing and developing novel targeted inhibitors.
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Medchemexpress LLC Mal-PEG3-NH2 | 2830214-77-0 | MFCD34184381 | 99.1% | 386.32 g·mol⁻¹ | C14H21F3N2O7 | 5 MG
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Mal-PEG3-NH2 TFA is a linear heterobifunctional polyethylene glycol (PEG) crosslinker supplied as the trifluoroacetic acid salt. It contains a maleimide at one terminus and a primary amine at the other, enabling orthogonal conjugation to thiols and amines for bioconjugation applications such as PROTAC and ADC linker design.
- Provides maleimide and amine reactive groups for orthogonal conjugation.
- Acts as a non-cleavable PEG spacer suitable for PROTAC and ADC constructs.
- High purity (~99.1%) and defined molecular weight (386.32 g·mol⁻¹).
- Viscous liquid form that dissolves in common organic solvents for easy handling.
- Long-term stability when stored under nitrogen at -80 °C in solvent; short-term stability at -20 °C.
- Offered in small research pack sizes for laboratory synthesis and linker optimization.
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Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | C16H26N4O9 | 100 MG
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Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker designed for synthesizing PROTACs. It features an Azide group, enabling click chemistry reactions like copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs
- Contains an Azide group for click chemistry reactions
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204191.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | 95.0% | 234.25 g/mol | C8H18N4O4 | 50 MG
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Aminooxy-PEG3-azide is a bifunctional PEG3 linker reagent containing an aminooxy group and an azide group, used for bioconjugation in ADC and PROTAC synthesis and for click chemistry conjugations.
- Contains an aminooxy group for oxime ligation.
- Contains an azide group for CuAAC and SPAAC click chemistry.
- Three-unit PEG spacer provides solubility and flexibility.
- High purity suitable for research applications.
- Stable when stored at -20°C in pure form.
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Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 5 G
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports. PROTACs consist of two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, and they exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- PROTACs degrade target proteins using the ubiquitin-proteasome system.
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Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 25 MG
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Facilitates selective degradation of target proteins through the intracellular ubiquitin-proteasome system
- Intended for research use only
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | ChemScene | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 10g | 582636019
NH2-PEG3-C2-Boc | ChemScene | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 10g | 582636019
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eMolecules 77544-68-4 | Tos-PEG3 | Medchem Express (US) | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 25g | 849371127
Tos-PEG3 | Medchem Express (US) | 77544-68-4 | MFCD18433414 | 304.360 | C13H20O6S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCO | 25g | 849371127
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Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG
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Azido-PEG3-C3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC M-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 1 G
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m-PEG3-Aminooxy is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. This product is intended strictly for research purposes and is not for patient use.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- For research use only
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Medchemexpress LLC NH-bis(PEG3-Boc) | 1814901-03-5 | 98.0% | C26H51NO10 | 50 MG
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NH-bis(PEG3-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules connect two different ligands: one for an E3 ubiquitin ligase and another for a target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based linker
- Essential for PROTAC synthesis
- Enables targeted protein degradation
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Medchemexpress LLC NH2-PEG3 | 6338-55-2 | 149.19 | 100 G
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NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker that belongs to the polyethylene glycol (PEG) linker family. It is used in the synthesis of PROTAC (β-NF-JQ1).
- PROTAC linker
- Can be used in the synthesis of PROTAC (β-NF-JQ1)
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eMolecules 252881-74-6 | H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 771325778
H2N-PEG3-CH2CH2COOtBu | Acrotein ChemBio Inc. | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 25g | 771325778
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