Ethyl Acetate
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Sigma Aldrich Fine Chemicals Biosciences Potassium acetate ACS reag100G
REAGENT Potassium acetate ACS reag100G
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Medchemexpress LLC Raphin1 acetate | 2242616-04-0 | 99.9% | 291.13 g/mol | C10H12Cl2N4O2 | 10MG
Raphin1 acetate is an orally bioavailable small-molecule inhibitor of the regulatory phosphatase PPP1R15B (R15B). It binds the R15B-PP1c holophosphatase with high affinity (Kd ≈ 33 nM), displays about 30-fold selectivity versus R15A-PP1c, and crosses the blood-brain barrier. The compound has shown reduction of molecular and organismal deficits in mouse models of protein misfolding disease and is supplied for research use in multiple small pack sizes.
- Selective inhibitor of PPP1R15B regulatory phosphatase.
- High-affinity binding to R15B-PP1c (Kd ≈ 33 nM).
- Approximately 30-fold selectivity over R15A-PP1c.
- Crosses the blood-brain barrier for CNS studies.
- High-purity research reagent suitable for in vitro and in vivo work.
- Available in multiple small pack sizes for dose-ranging studies.
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Sigma Aldrich Fine Chemicals Biosciences Ethyl acetate/Ethanol 3:1 (v/v) solution (Ethyl acetate solution with 26.2% v/v SDA 35A), suitable for HPLC | 2.5L
Ethyl acetate/Ethanol 3:1 (v/v) solution (Ethyl acetate solution with 26.2% v/v SDA 35A), suitable for HPLC | 2.5L
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Sigma Aldrich Fine Chemicals Biosciences Sodium acetate ACS reagent25KG
REAGENT Sodium acetate ACS reagent25KG
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Sigma Aldrich Fine Chemicals Biosciences Sodium acetate ACS reagent100G
REAGENT Sodium acetate ACS reagent100G
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Sigma Aldrich Fine Chemicals Biosciences Zinc acetate dihydrate pur250G
ZINC Zinc acetate dihydrate pur250G