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Available in various chemical compositions, quantities, boiling points, and reagent grades, solvent blends combine solubility properties of their individual solvent components to create versatile solvents for specific industrial and laboratory applications.
DCA (Sodium dichloroacetate) a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 M for PDK2 and PDK4 respectively has been shown to derepress Na -K -2Cl- cotransporter and a mitochondrial potassium-ion channel axis Sodium dichloroacetate increases reactive oxygen species (ROS) generation triggers apoptosis in cancer cells and inhibits tumor growth
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