Prenol lipids
Medchemexpress LLC Genipin | 6902-77-8 | MFCD00888600 | 99.8% | 226.23 | 25 MG
Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells. This compound exhibits various bioactivities, making it suitable for a range of research applications.
- Modulates proteins
- Antitumor properties
- Anti-inflammation capabilities
- Immunosuppressive effects
- Antithrombosis activity
- Protects hippocampal neurons
- Used for type 2 diabetes research
Apexbio Technology LLC Glycyrrhizic acid 1405-86-3 20mg
Glycyrrhizic acid (CAS 1405-86-3) is a triterpenoid saponin antagonist targeting high mobility group box 1 (HMGB1) and inhibitor of monoamine oxidase (MAO) as well as cytochrome P450 enzymes (CYP3A4 CYP2C9 CYP2C19) and 11 -hydroxysteroid dehydrogenase type 2 (11 -HSD2) It is designed to antagonize HMGB1-mediated pro-inflammatory responses and oxidative stress inhibit the enzymatic activity of MAO and 11 -HSD2 and modulate cytochrome P450-mediated metabolism Glycyrrhizic acid exerts its biological activity primarily through competitive inhibition of these enzymes It demonstrates MAO inhibition with an IC50 of approximately 0 16 M and competitively inhibits CYP3A4 (IC50 8 2 M) CYP2C9 ( 42 9 M) and CYP2C19 ( 40 3 M) Based on these pharmacological properties glycyrrhizic acid holds research potential in anti-inflammatory pathways enzyme inhibition and glucose metabolic modulation
Medchemexpress LLC Mait-203 acetate | 98.0% | 2517.23 | 5 MG
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic that inhibits APC-Asef interaction and represses colorectal cancer cell migration and invasion.
- Potently inhibits APC-Asef interaction.
- Binds APC-ARM with Ki of 0.015 μM and Kd of 0.036 μM.
- Represses migration and invasion of colorectal cancer cells.
- Reduces Asef-APC interaction in HEK293T cells.
- Attenuates SW480 and HCT116 cell migration.
- Decreases active CDC42 in SW480 cells.
- Keep container tightly sealed in cool, well-ventilated area.
- Keep away from direct sunlight and sources of ignition.
- Store powder at -80°C for 2 years or -20°C for 1 year.
- Store in solvent at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture).
- Ship at room temperature if less than 2 weeks.
Selleck Chemical LLC Vitamin K1 S4698-25mg
Vitamin K1 (Phyllohydroquinone Phylloquinone Phytomenadione Phytonadione) made by plants is a major type of dietary vitamin K which is well-known for its role in blood clotting Vitamin K1 is directly involved in photosynthesis
TARGETMOL CHEMICALS INC Oleanolic Acid 1G
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants. Purity 98.4%
Alkali Scientific CellPro™ 100X Vitamin solution, 100ml, 10/Case
Growth supplement for cell culture medium. Supplement serum- and protein-free media with CellPro™ 100X Vitamin Solution.
Medchemexpress LLC (rel)-AR234960 | 1408311-94-3 | HY-120006A | 98.95% | 555.62 | 10 MG
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. It activates the downstream ERK1/2 signaling pathway, leading to the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes. This compound promotes collagen synthesis in cardiac fibroblasts via the MAS-ERK1/2-CTGF pathway and exacerbates extracellular matrix remodeling. It regulates the expression of cardiac fibrosis-related genes and can be utilized in heart failure research.
- Selective and competitive MAS receptor agonist
- Activates ERK1/2 signaling pathway
- Induces CTGF and collagen gene expression
- Promotes collagen synthesis in cardiac fibroblasts
- Regulates cardiac fibrosis-related genes
- Useful in heart failure research
Medchemexpress LLC RVG-Cys acetate | 99.7% | 3369.77 (free acid) | 5 MG
RVG-Cys acetate is a peptide derived from rabies virus glycoprotein (RVG29). It is designed with a Cys attachment to facilitate subsequent conjugation and enhances the specific targeted delivery of proteins in brain tissue and neurons. This product is for research use only.
- Peptide derived from rabies virus glycoprotein (RVG29)
- Cys attached for subsequent conjugation
- Enhances specific targeted delivery of proteins
- Targets brain tissue and neurons
- For research use only
Medchemexpress LLC Docetaxel | 114977-28-5 | 99.9% | C43H53NO14 | 1 ML
Docetaxel is a microtubule depolymerization inhibitor with an IC50 of 0.2 μM. It attenuates the effects of bcl-2 and bcl-xL gene expression, leading to cell cycle arrest at G2/M and subsequent apoptosis. This compound demonstrates anti-cancer activity.
- Microtubule depolymerization inhibitor
- Attenuates effects of bcl-2 and bcl-xL gene expression
- Arrests cell cycle at G2/M
- Leads to cell apoptosis
- Demonstrates anti-cancer activity