Organic Acids
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Medchemexpress LLC Tiglic acid | 80-59-1 | 99.97% | 100.12 | 5 G
Tiglic acid is a monocarboxylic unsaturated organic acid that can be isolated from croton oil. It agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity, making it suitable for research into obesity, diabetes, and inflammatory diseases.
- Agonizes FFA2
- Upregulates PYY expression
- Derivatives show anti-inflammatory activity
- Useful in obesity research
- Useful in diabetes research
- Useful in inflammatory diseases research
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eMolecules AstaTech / 22-DIFLUORO-2-(FLUOROSULFONYL)ACETIC ACID / 5g / 351646826 / P17348 / 95.000 / 1717-59-5 / MFCD01320807 / 178.080 / C2HF3O4S
AstaTech / 22-DIFLUORO-2-(FLUOROSULFONYL)ACETIC ACID / 5g / 351646826 / P17348 / 95.000 / 1717-59-5 / MFCD01320807 / 178.080 / C2HF3O4S
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Medchemexpress LLC Bpam344 | 1204572-55-3 | 99.7% | 10 MG
BPAM344 is a kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a positive allosteric modulator (PAM). It functions by potentiating glutamate-evoked currents and significantly decreasing desensitization kinetics.
- Potentiates glutamate-evoked currents of GluK2a 21-fold at 200 μM, with an EC50 of 79 μM
- Significantly decreases desensitization kinetics
- Potentiates peak current amplitude of KAR subunits GluK3a (59-fold), GluK2a (15-fold), GluK1b (5-fold), and AMPA receptor subunit GluA1i (5-fold)