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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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N-decanoyl-L-homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL). It can inhibit primary root growth in Arabidopsis, triggering an immediate increase in cytosolic free Ca2+ and reactive oxygen species (ROS), increasing mitogen-activated protein kinase 6 (MPK6) activity, and inducing nitric oxide (NO) production in Arabidopsis roots.
Formula: C14H25NO3
Appearance: Solid, white to off-white
Initial source: Microorganisms
Reduces primary root growth in Arabidopsis
Promotes lateral root formation in Arabidopsis
Stimulates spore germination of Galactomyces geotrichum
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Otilonium bromide is an orally active mAChR inhibitor and smooth muscle relaxant. It can interfere with the mobilization of calcium in intestinal smooth muscle and is used for research on irritable bowel syndrome.
Inhibits acetylcholine-induced human colonic crypt calcium signals in a dose-dependent manner with an IC50 of 880 nM.
Inhibits Ca2+ uptake in bovine chromaffin cells at 30 μM.
Targets mAChR and is involved in GPCR/G Protein and Neuronal Signaling pathways.
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N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate utilized in applications such as antisense oligonucleotides and mRNA modification. It functions as a key monomer for synthesizing 2'-O-methyl oligoribonucleotides, allowing the final product to form stable double strands with complementary RNA and resist degradation by nucleases. It is primarily used in molecular biology research.
Used for antisense oligonucleotides and mRNA modification.
Serves as a key monomer for synthesizing 2'-O-methyl oligoribonucleotides.
Enables stable double strand formation with complementary RNA.
Resists degradation by nucleases.
Used in molecular biology research and pre-mRNA splicing mechanisms studies.
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Ipratropium bromide is a muscarinic receptor antagonist that relaxes smooth muscle. It is designed for research applications in areas such as chronic obstructive pulmonary disease (COPD) and asthma.
Muscarinic receptor antagonist
Relaxes smooth muscle
Suitable for research in COPD
Suitable for research in asthma
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A benzyolated derivative of cytidine; a substrate of UCK1 and UCK2; has been used in the synthesis of 2ʹ-OH protecting groups for solid-phase RNA synthesis and synthetic oligonucleotides for UV light-induced and targeted gene silencing in zebrafish embryos
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A thioester phospholipase substrate; exhibits 10-13 fold less activity for the porcine pancreatic and bee venom sPLA2 enzymes compared to diheptanoyl thio-PC
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