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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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DOTAP chloride is an effective cationic lipid used for transient and stable transfection of DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides). It facilitates genetic material delivery without the need for a helper lipid.
Useful for transient and stable transfection of DNA and modified nucleic acids
Cationic lipid
Does not require a helper lipid for transfection
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Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract. It effectively relieves pain, diarrhea, and intestinal discomfort, providing good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients.
Inhibits GM-CSF or CXCL1/CXCL2 induced neutrophil migration and ROS production.
Inhibits GM-CSF induced expression of cytokines (IL-1β, IL-6, and TNF-α) in primed neutrophils.
Inhibits the contractile response to ACh or KCl in colonic circular muscle.
Inhibits excessive systemic inflammation in Lipopolysaccharide-induced mice.
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1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine is a zwitterionic phospholipid used as a lipid component in model membranes and for preparing liposomes and other lipid assemblies in biochemical and biophysical research.
High purity suitable for research applications (99.8%).
White to off-white solid appearance and consistent quality.
Molecular formula C42H82NO8P; molecular weight 760.08 g/mol.
Suitable for liposome synthesis and membrane model systems.
Powder storage: -20°C for up to 3 years; in solvent: -80°C for 6 months, -20°C for 1 month.
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Cimetropium Bromide (DA-3177) is an mAChR antagonist developed for the long-term treatment of irritable bowel syndrome. This compound is intended for research use only and functions as a competitive antagonist of muscarinic-mediated contractions in isolated colonic preparations.
Acts as a competitive antagonist of muscarinic-mediated contractions.
Exhibits potent antimuscarinic effects on longitudinal muscle preparations.
Effectively inhibits large bowel motility in vivo.
Suitable for research applications related to irritable bowel syndrome.
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Butyryl-L-carnitine chloride is the chloride salt of the acylcarnitine Butyryl-L-carnitine, provided as a research-grade chemical for biochemical and in vitro studies of acylcarnitine metabolism.
High chemical purity (98.07%).
Chemical formula C11H22ClNO4 and molecular weight 267.75.
Chloride salt of Butyryl-L-carnitine for biochemical and metabolic studies.
Available in small research pack sizes suitable for assay development.
For research use only; not for human or clinical use.
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