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3-(2-furoyl)quinoline-2-carboxaldehyde is a fluorescent quinoline-derived aldehyde used as a fluorogenic labeling reagent in biochemical and analytical applications. It is supplied as a solid with high reported purity and is commonly used to derivatize primary amines to produce fluorescent products for HPLC, microscopy, and other assays.
Fluorogenic reagent for labeling primary amines.
High purity suitable for analytical work.
Supplied as an off-white to light yellow solid for ease of handling.
Available in small mass quantities for research use (e.g., 10 mg).
Stable when stored protected from light at low temperatures.
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Chemical. CAS 155862-89-8. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance.
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Chemical. CAS 155862-91-2. Formula C18H16BrN3O2S. MW 418.31. Synthetic. Class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Relatively low extinction coefficient Epsilon∼ >20,000 in EtOH.
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Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
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