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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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N-(4-Nitrobenzoyl)glycine is an amino acid derivative of glycine intended for laboratory research. Manufacturer data list the molecular formula and molecular weight, and report high purity; the material is supplied in small-scale packages for synthesis and analytical work. For research use only.
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Umeclidinium bromide is a novel mAChR antagonist with an affinity (Ki) for cloned human M1-M5 mAChRs ranging from 0.05 to 0.16 nM. It inhibits the human ether-a-go-go-related gene channel tail current in a concentration-dependent manner.
Novel mAChR antagonist
Inhibits human ether-a-go-go-related gene channel tail current
Shows slow functional reversibility at cloned human M3 mAChRs
Shows slow functional reversibility at endogenous mAChR in isolated human bronchus
For research use only
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1-Palmitoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine (16:0 Lyso PC) used in biochemical and cellular research. It is an abundant lysophospholipid with reported proinflammatory activity and is employed in studies of lipid signaling, inflammation, and atherosclerosis. The compound is supplied as a research-grade powder with molecular formula C24H50NO7P and molecular weight 495.63 g·mol⁻¹.
High purity (99.9%) suitable for analytical and in vitro studies.
Powder form convenient for storage and solution preparation.
Useful for studies of lipid signaling, inflammation, and atherosclerosis.
Soluble in common organic solvents for assay compatibility.
Available in multiple pack sizes to support different experimental scales.
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Umeclidinium bromide(GSK573719A) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD)
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1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid. It can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH, making it suitable for various research applications.
PE-based synthetic phospholipid
Forms stable bilayers at physiological pH
Can be used in drug delivery research
Appears as white to off-white solid
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A chromogenic substrate for PLA2; hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB with an absorbance maximum at 412 nm; has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system
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Umeclidinium bromide is a novel muscarinic acetylcholine receptor (mAChR) antagonist. It exhibits high affinity for human M1-M5 mAChRs, with Ki values ranging from 0.05 to 0.16 nM. This compound demonstrates antagonist activity at the human cloned muscarinic M3 receptor and inhibits the human ether-a-go-go-related gene (hERG) channel tail current.
Targets mAChR1 and mAChR5.
Inhibits acetylcholine-induced calcium mobilization in CHO cells.
Demonstrates slow functional reversibility at M3 mAChRs.
Inhibits human ether-a-go-go-related gene channel tail current.
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A chromogenic substrate for PLA2; hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB with an absorbance maximum at 412 nm; has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system
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Butylscopolamine Bromide (Scopolamine Butylbromide (-)-Scopolamine butylbromide Hyoscine butylbromide) is a peripherally acting antimuscarinic anticholinergic agent used as an abdominal-specific antispasmodic
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Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant. It is used in modern anaesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Reduced twitch tensions in normal and pretreated diaphragms in a concentration-dependent fashion.
ED95 is similar for children and adults.
Duration of action is similar to vecuronium, shorter for children than adults.
Readily reversed with conventional doses of cholinesterase-inhibiting drugs.
Facilitates endotracheal intubation.
Provides skeletal muscle relaxation during surgery or mechanical ventilation.
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