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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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7-iodo-7-deaza-2'-deoxyguanosine is a halogenated deoxyguanosine nucleoside analog used as a building block in nucleic acid chemistry. It is used in oligonucleotide synthesis and sequencing, and can be converted to its triphosphate form for enzymatic incorporation.
High purity: 99.8%.
Chemical formula: C11H13IN4O4.
Molecular weight: 392.15 g·mol⁻¹.
Suitable for DNA synthesis and sequencing applications.
Can be triphosphorylated for enzymatic incorporation into DNA.
Available as a 250 mg package.
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Iodo-PEG3-N3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs employ the intracellular ubiquitin-proteasome system to specifically degrade target proteins.