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Organic compounds that are derived from or have a benzene group in their molecular structure. Benzene is an aromatic organic molecule composed of 6 carbon atoms and 6 hydrogen atoms that form a ring. Includes derivatives and substituted molecules.
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Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase and is used as a depigmenting agent. It is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possessing anti-oxidant, anti-inflammatory, and anti-tumor properties.
Inhibits the viability of B16 murine melanoma cells in a time- and dose-dependent manner.
Increases the apoptosis rate of B16 murine melanoma cells.
Exhibits protective effects on isoproterenol-induced cardiac hypertrophy in mice.
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XP-524 is a potent BET and EP300 inhibitor that shows great tumoricidal activity in vivo. It prevents KRAS-induced neoplastic transformation and extends survival in aggressive PDAC mouse models. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes, making it a potential research tool for pancreatic ductal adenocarcinoma (PDAC).
Potent BET and EP300 inhibitor
Exhibits significant tumoricidal activity in vivo
Prevents KRAS-induced neoplastic transformation
Prolongs survival in aggressive PDAC mouse models
Enhances self-peptide presentation
Promotes tumor recruitment of cytotoxic T lymphocytes
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MTR-106 is a potent and orally active G-quadruplex stabilizer and RNA polymerase I inhibitor. It induces apoptosis and inhibits cell growth, and can be used in research of cancer.
Potent and orally active G-quadruplex stabilizer
RNA polymerase I inhibitor
Induces apoptosis
Inhibits cell growth
Can be used in research of cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More