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Organic compounds that are derived from or have a benzene group in their molecular structure. Benzene is an aromatic organic molecule composed of 6 carbon atoms and 6 hydrogen atoms that form a ring. Includes derivatives and substituted molecules.
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Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ1-42 β-sheets formation and tau aggregation. With KD values of 160 μM for Aβ1-42 and 337 μM for tau, it effectively permeates the blood-brain barrier. Studies have shown its significant ability to reduce tau aggregation foci in HEK-293 T cells at a concentration of 1 μM for 24 hours. The compound achieves 84.7%-99.5% inhibition of Aβ1-42 aggregation and 71.2%-101.8% inhibition of tau aggregation by preventing β-sheet formation and through noncovalent interactions with both Aβ1-42 and tau.
Potent Aβ1-42 β-sheets formation inhibitor
Effective tau aggregation inhibitor
Permeates the blood-brain barrier
Reduces tau aggregation foci in HEK-293 T cells
Prevents β-sheet formation
Acts via noncovalent interactions with Aβ1-42 and tau
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AC-94149 is a substituted nitro compound used as an intermediate in herbicide synthesis and agrochemical research. It has the molecular formula C6H12N2, molecular weight 112.17 g/mol, CAS number 13893-53-3, and is typically supplied at 90.0% purity in small research pack sizes.
Used as an intermediate in herbicide synthesis and agrochemical research
Typical purity of 90.0% suitable for research applications
Available in small pack sizes for lab-scale work
Provided with datasheet, certificate of analysis, and safety data sheet
Molecular formula C6H12N2 and molecular weight 112.17 g/mol
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More