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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ETC-159 is a potent, orally available porcupine (PORCN) inhibitor used in research to block Wnt ligand secretion and Wnt/β-catenin signaling. It inhibits β-catenin reporter activity with a reported IC50 of 2.9 nM and has been evaluated in preclinical and early clinical studies for Wnt-dependent cancers. Typical supplier purity is ≥95% and the compound is supplied as a crystalline solid.
Potent PORCN inhibition with low nanomolar activity.
Orally bioavailable for in vivo research applications.
Blocks Wnt ligand secretion and downstream β-catenin signaling.
Reported β-catenin reporter IC50 ~2.9 nM.
High purity (≥95%) and crystalline solid form.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More