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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ETC-159 is a potent, orally available porcupine (PORCN) inhibitor used in research to block Wnt ligand secretion and Wnt/β-catenin signaling. It inhibits β-catenin reporter activity with a reported IC50 of 2.9 nM and has been evaluated in preclinical and early clinical studies for Wnt-dependent cancers. Typical supplier purity is ≥95% and the compound is supplied as a crystalline solid.
Potent PORCN inhibition with low nanomolar activity.
Orally bioavailable for in vivo research applications.
Blocks Wnt ligand secretion and downstream β-catenin signaling.
Reported β-catenin reporter IC50 ~2.9 nM.
High purity (≥95%) and crystalline solid form.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a small-molecule topoisomerase I inhibitor used in research as an antibody-drug conjugate (ADC) payload; the compound shows demonstrated activity in vitro and in vivo and is supplied for laboratory studies.
High purity (98.7%) suitable for research applications.
Solid form, provided as a dry material for formulation or conjugation.
Molecular formula C26H23N3O6; molecular weight 473.48 g·mol⁻¹.
Available in 10 mg pack sizes for laboratory-scale experiments.
Store at -20°C and protect from light; in solvent: -80°C (6 months), -20°C (1 month).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More