Hydrocarbons
Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | MFCD11040976 | 99.4% | 431.91 g/mol | C22H26ClN3O4 | 10 MG
Bay 65-1942 hydrochloride is an ATP-competitive, selective inhibitor of IKKβ used in research to probe NF-κB signaling and inflammatory pathways. It is supplied as the hydrochloride salt to improve solubility and handling, and is intended for use in biochemical and cell-based assays.
- Selective inhibition of IKKβ for pathway interrogation.
- ATP-competitive mode of action suitable for biochemical assays.
- High reported purity for reproducible results.
- Hydrochloride salt with improved solubility in DMSO and aqueous buffers.
- Suitable for biochemical and cell-based assay applications.
eMolecules 1942-46-7 | 5-Decyne | Oakwood Chemicals | MFCD00027277 | 138.254 | C10H18 | 98.000 | CCCCC#CCCCC | 5g | 480155740
5-Decyne | Oakwood Chemicals | 1942-46-7 | MFCD00027277 | 138.254 | C10H18 | 98.000 | CCCCC#CCCCC | 5g | 480155740
Medchemexpress LLC 9-cis-β-Carotene | 13312-52-2 | 99.0% | 536.87 | 500 UG
9-cis-β-Carotene is a precursor of retinal, cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo, with potential for the study of congenital stationary night blindness and fundus albipunctatus.
- Inhibits photoreceptor degeneration.
- Restores retinal function in vivo.
- Potential for studying congenital stationary night blindness.
- Potential for studying fundus albipunctatus.
- Prevents S- and M-cone degeneration in eye cups.
- Rescues retinal function and preserves cone structure in a mouse model of retinoid cycle defect.
![Medchemexpress LLC (S)-N-((S)-1-cyclohexyl-2-(3-morpholinopropanamido)ethyl)-3-(6-isopropylbenzo[d]thiazol-2-yl)-2-prop | 2245887-38-9 | 98.1% | 585.80 | C31H47N5O4S | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236787.png-250.jpg)
Medchemexpress LLC (S)-N-((S)-1-cyclohexyl-2-(3-morpholinopropanamido)ethyl)-3-(6-isopropylbenzo[d]thiazol-2-yl)-2-prop | 2245887-38-9 | 98.1% | 585.80 | C31H47N5O4S | 100MG
DI-591 is a cell-permeable, high-affinity small-molecule inhibitor of the DCN1-UBC12 interaction. It binds human DCN1 and DCN2 with low nanomolar affinity (Ki ≈ 10-12 nM) and selectively inhibits neddylation of cullin 3, making it a useful chemical probe for studying cullin 3-dependent CRL biology and related cellular processes.
- High affinity, low nanomolar binding to DCN1 and DCN2.
- Cell-permeable small-molecule probe suitable for cellular assays.
- Selectively inhibits neddylation of cullin 3 with minimal effect on other cullins.
- Available as powder and as a 10 mM solution in DMSO for convenience.
- High purity for research use and stability under recommended storage conditions.
Apexbio Technology LLC ADH-503 2055362-74-6 1mL(10 mM in DMSO)
ADH-503 (CAS 2055362-74-6) also known as (Z)-Leukadherin-1 choline is an orally bioavailable small molecule that functions as an allosteric agonist This compound modulates macrophage phenotypes by promoting repolarization of tumor-associated macrophages resulting in a reduction of immunosuppressive myeloid cell infiltration within the tumor microenvironment Additionally ADH-503 has been shown to enhance dendritic cell responses These properties make ADH-503 a valuable tool for investigating macrophage regulation and immune modulation in the context of cancer research