Organic acids and derivatives
Apexbio Technology LLC Baricitinib phosphate(Synonyms: Baricitinib phosphate, Olumiant phosphate, LY3009104 phosphate, INCB028050 phosphate), 5mg, CAS: 1187595-84-1.
Baricitinib phosphate (CAS 1187595-84-1) known as INCB028050 is an orally bioavailable small molecule inhibitor targeting Janus kinases JAK1 and JAK2 It selectively inhibits JAK1 and JAK2 with IC50 values of approximately 5 9 nM and 5 7 nM respectively exhibiting roughly 10-fold lower potency towards JAK3 and Tyk2 and lacking inhibition against c-Met and Chk2 By suppressing JAK1/2-mediated signaling baricitinib phosphate reduces signal transduction induced by proinflammatory cytokines such as IL-6 and IL-23 in vitro Preclinical studies in rodent arthritis models indicate notable therapeutic activity with minimal evidence of adverse hematological or immunosuppressive effects This compound is used widely in biomedical research for investigating inflammatory pathways in autoimmune disease models
TARGETMOL CHEMICALS INC 6-Acryloyloxyhexyl phosphate
Also available in 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 6-Acryloyloxyhexyl phosphater (PA21) is a novel phosphate-binding agent, which is an iron-based reagent, and can be used for the treatment of hyperphosphatemia in chronic kidney disease. Purity ≥98%
Medchemexpress LLC Mefenpyr-diethyl | 135590-91-9 | 99.5% | 373.23 | 10 G
Mefenpyr-diethyl is a pyrazoline-type herbicide safener that functions to enhance lipid biosynthesis. It effectively prevents herbicide-induced phytotoxic damage caused by herbicides like fenoxaprop-p-ethyl and mesosulfuron-methyl, thereby protecting cereal crops, including wheat. It significantly increases lipid content in wheat, whether applied alone or in combination with fenoxaprop-p-ethyl. Its mechanism of action does not involve inducing glutathione S-transferase (GST) activity in wheat.
- Functions as a pyrazoline-type herbicide safener
- Enhances lipid biosynthesis
- Prevents herbicide-induced phytotoxic damage in cereal crops
- Protects against damage from herbicides like fenoxaprop-p-ethyl and mesosulfuron-methyl
- Significantly increases lipid content in wheat
- Does not involve inducing glutathione S-transferase (GST) activity in wheat
- Alters glutathione S-transferase (GST) activity in wheat cultivars
Medchemexpress LLC Diethyl pyrocarbonate | 1609-47-8 | 98.0% | 25 G
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. It has been found useful in vitro as an agent relatively specific for binding to imidazole of histidine. It inhibits central chemosensitivity in rabbits and can modify Ser, Thr, His, and Tyr residues. It can also be used for modeling purposes.
- Potent, orally active, non-specific chemical inhibitor of RNase.
- Useful in vitro as an agent relatively specific for binding to imidazole of histidine.
- Inhibits central chemosensitivity in rabbits.
- Can modify Ser, Thr, His, and Tyr residues.
- Can be used for modeling.
Medchemexpress LLC Diethyl 2-bromoglutarate | 7209-00-9 | 91.0% | 267.12 | 50 G
Diethyl 2-bromoglutarate is a drug intermediate for the synthesis of various active compounds. This product is for research use only.
- Target: drug intermediate
- Pathway: others
- For research use only
Medchemexpress LLC Fingolimod phosphate (FTY720 phosphate) | 402615-91-2 | C19H34NO5P | 1 ML
Fingolimod phosphate is an orally active sphingosine 1-phosphate (S1P) receptor agonist that promotes the neuroprotective effects of microglia. It is used in research for multiple sclerosis and neurologic diseases.
- Orally active S1P receptor agonist
- Promotes neuroprotective effects of microglia
- Used in research for multiple sclerosis
- Used in research for neurologic diseases
- Purity of 99.18%
- Appears as a white to off-white solid
Medchemexpress LLC Carbamoyl phosphate dilithium salt | 1866-68-8 | 152.89 | 5 MG
Carbamoyl phosphate dilithium salt is an antisickling agent that plays a significant role in the urea cycle. It carbamylates the amino-terminal valine residues of hemoglobin S in erythrocytes, interfering with the sickling phenomenon. This compound exhibits toxicity due to the lithium cation.
- Antisickling agent
- Plays a significant role in the urea cycle
- Carbamylates amino-terminal valine residues of hemoglobin S
- Interferes with the sickling phenomenon
- Intended for research use only
Medchemexpress LLC ODN 2216 sodium | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 100 MG
ODN 2216 sodium | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G), sodium salt | 100 MG
![eMolecules 10049-21-5 | Sodium phosphate monobasic monohydrate ACS granular | Oakwood Chemicals | MFCD00149208 | 137.991 | H4NaO5P | 98.000 | O.[Na+].OP(O)([O-])=O | 100g | 480150908](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000473227.jpg-250.jpg)
eMolecules 10049-21-5 | Sodium phosphate monobasic monohydrate ACS granular | Oakwood Chemicals | MFCD00149208 | 137.991 | H4NaO5P | 98.000 | O.[Na+].OP(O)([O-])=O | 100g | 480150908
Sodium phosphate monobasic monohydrate ACS granular | Oakwood Chemicals | 10049-21-5 | MFCD00149208 | 137.991 | H4NaO5P | 98.000 | O.[Na+].OP(O)([O-])=O | 100g | 480150908
eMolecules 108549-23-1 | DIBENZYL N,N-DIISOPROPYLPHOSPHORAMIDITE | AstaTech | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 100g | 528280391
DIBENZYL N,N-DIISOPROPYLPHOSPHORAMIDITE | AstaTech | 108549-23-1 | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 100g | 528280391
eMolecules 108549-23-1 | Dibenzyl N,N-Diisopropylphosphoramidite | Accela ChemBio (ASD) | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 5g | 448669937
Dibenzyl N,N-Diisopropylphosphoramidite | Accela ChemBio (ASD) | 108549-23-1 | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 5g | 448669937
eMolecules 108549-23-1 | Dibenzyl N,N-Diisopropylphosphoramidite | Accela ChemBio (ASD) | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 10g | 485060881
Dibenzyl N,N-Diisopropylphosphoramidite | Accela ChemBio (ASD) | 108549-23-1 | MFCD00191988 | 345.423 | C20H28NO2P | 95.000 | CC(C)N(C(C)C)P(OCc1ccccc1)OCc1ccccc1 | 10g | 485060881