Organoheterocyclic compounds
2-Amino-5-methylthiazole 98.0+%, TCI America™
CAS: 7305-71-7 Molecular Formula: C4H6N2S Molecular Weight (g/mol): 114.166 MDL Number: MFCD00078317 InChI Key: GUABFMPMKJGSBQ-UHFFFAOYSA-N Synonym: 2-amino-5-methylthiazole,5-methylthiazol-2-amine,2-thiazolamine, 5-methyl,2-amino-5-methyl-thiazole,thiazole, 2-amino-5-methyl,5-methyl-2-thiazolamine,5-methyl-2-aminothiazole,unii-7rab78af2p,2-amino-5-methyl thiazole,meloxicam related compound b PubChem CID: 351770 IUPAC Name: 5-methyl-1,3-thiazol-2-amine SMILES: CC1=CN=C(S1)N
1-(3-Methoxyphenyl)piperazine 98.0+%, TCI America™
CAS: 16015-71-7 Molecular Formula: C11H16N2O Molecular Weight (g/mol): 192.262 MDL Number: MFCD00040733 InChI Key: PZIBVWUXWNYTNL-UHFFFAOYSA-N Synonym: 1-3-methoxyphenyl piperazine,n-3-methoxyphenyl piperazine,1-3-methoxyphenyl-piperazine,unii-6lcp52962g,1-3-methoxy-phenyl-piperazine,chembl59597,piperazine, 1-3-methoxyphenyl,3-methoxy-1-piperazinylbenzene,pubchem8585,3-meopp PubChem CID: 81430 IUPAC Name: 1-(3-methoxyphenyl)piperazine SMILES: COC1=CC=CC(=C1)N2CCNCC2
2,5-Diphenyloxazole 99.0+%, TCI America™
CAS: 92-71-7 Molecular Formula: C15H11NO Molecular Weight (g/mol): 221.26 MDL Number: MFCD00005306 InChI Key: CNRNYORZJGVOSY-UHFFFAOYSA-N Synonym: 2,5-diphenyloxazole,oxazole, 2,5-diphenyl,tritosol,2,5-diphenyl-oxazole,ppo scintillator,dpo scintillator,usaf ek-6775,ppo van,ppo,ppo scintillator van PubChem CID: 7105 IUPAC Name: 2,5-diphenyl-1,3-oxazole SMILES: O1C(=CN=C1C1=CC=CC=C1)C1=CC=CC=C1
Cytosine 98.0+%, TCI America™
CAS: 71-30-7 Molecular Formula: C4H5N3O Molecular Weight (g/mol): 111.10 MDL Number: MFCD00006034 InChI Key: OPTASPLRGRRNAP-UHFFFAOYSA-N Synonym: cytosine,4-amino-2-hydroxypyrimidine,cytosinimine,2 1h-pyrimidinone, 4-amino,4-amino-2 1h-pyrimidinone,4-aminopyrimidin-2 1h-one,6-aminopyrimidin-2 1h-one,2 1h-pyrimidinone, 6-amino,cyt,4-amino-2-oxo-1,2-dihydropyrimidine PubChem CID: 597 ChEBI: CHEBI:16040 IUPAC Name: 6-amino-1,2-dihydropyrimidin-2-one SMILES: NC1=CC=NC(=O)N1
![1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-6969-71-7.jpg-250.jpg)
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one 98.0+%, TCI America™
CAS: 6969-71-7 Molecular Formula: C6H5N3O Molecular Weight (g/mol): 135.126 MDL Number: MFCD00022632 InChI Key: LJRXNXBFJXXRNQ-UHFFFAOYSA-N Synonym: 1,2,4-triazolo 4,3-a pyridin-3 2h-one,1,2,4 triazolo 4,3-a pyridin-3 2h-one,2h-1,2,4 triazolo 4,3-a pyridin-3-one,1,2,4 triazolo 4,3-a pyridin-3-ol,s-triazolo 4,3-a pyridin-3-ol,2h,3h-1,2,4 triazolo 4,3-a pyridin-3-one,3-hydroxytriazolo 4,3-a pyridine,1,2,4-triazolo-4,3,a pyridin-3 2h-one,4-hydro-2h-1,2,4-triazolino 4,3-a pyridin-3-one PubChem CID: 81431 IUPAC Name: 2H-[1,2,4]triazolo[4,3-a]pyridin-3-one SMILES: C1=CC2=NNC(=O)N2C=C1
Trioxsalen 98.0+%, TCI America™
CAS: 3902-71-4 Molecular Formula: C14H12O3 Molecular Weight (g/mol): 228.25 MDL Number: MFCD00005010 InChI Key: FMHHVULEAZTJMA-UHFFFAOYSA-N Synonym: trioxsalen,trioxysalen,trisoralen,trimethylpsoralen,4,5',8-trimethylpsoralen,elder 8011,trioxisaleno,trioxysalene,trioxysalenum,2',4,8-trimethylpsoralen PubChem CID: 5585 ChEBI: CHEBI:28329 IUPAC Name: 2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one SMILES: CC1=CC2=CC3=C(OC(=O)C=C3C)C(C)=C2O1
Pilocarpine Hydrochloride 98.0+%, TCI America™
CAS: 54-71-7 Molecular Formula: C11H17ClN2O2 Molecular Weight (g/mol): 244.72 MDL Number: MFCD00012722 InChI Key: RNAICSBVACLLGM-GNAZCLTHSA-N Synonym: pilocarpine hydrochloride,+-pilocarpine hydrochloride,pilocarpal,pilocar,pilocar smp,almocarpine,pilomiotin,pilovisc,pilocel,pilocarpine hcl PubChem CID: 5909 IUPAC Name: hydrogen (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one chloride SMILES: [H+].[Cl-].CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O
Ethyl 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylate 98.0+%, TCI America™
CAS: 112811-71-9 Molecular Formula: C16H15F2NO4 Molecular Weight (g/mol): 323.296 MDL Number: MFCD05864419 InChI Key: XPAOPAPDCRLMTR-UHFFFAOYSA-N Synonym: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester PubChem CID: 10758239 IUPAC Name: ethyl 1-cyclopropyl-6,7-difluoro-8-methoxy-4-oxoquinoline-3-carboxylate SMILES: CCOC(=O)C1=CN(C2=C(C(=C(C=C2C1=O)F)F)OC)C3CC3
Chem-Impex International, Inc. Cytosine | 71-30-7 | MFCD00006034 | 100G
Cytosine, 71-30-7, MFCD00006034, 100G
Apexbio Technology LLC AEG 3482 63735-71-7 10mg
AEG 3482 (CAS 63735-71-7) is a small molecule inhibitor that impedes Jun N-terminal kinase (JNK)-dependent apoptotic signaling By interfering with the JNK pathway which is implicated in neuronal cell death and activated in models of Alzheimer s and Huntington s disease AEG 3482 blocks apoptosis induced by p75 neurotrophin receptor (p75NTR) or its adaptor NRAGE The compound promotes expression of heat shock protein 70 (HSP70) an endogenous JNK inhibitor and requires HSP70 accumulation for its anti-apoptotic effect AEG 3482 is used as a research tool for studying neuronal apoptosis and has potential in investigating neuroprotection strategies
Apexbio Technology LLC o-Phenanthroline 66-71-7 10g
o-Phenanthroline (CAS 66-71-7) is a cell-permeable metal chelator that functions as a non-selective inhibitor of matrix metalloproteinases (MMPs) which are zinc-dependent enzymes implicated in extracellular and intracellular matrix remodeling under stress conditions It has been shown to suppress MMP-2-mediated proteolysis of nuclear lamins in vitro indicating a direct effect on structural nuclear proteins In myocardial ischemia-reperfusion models o-Phenanthroline treatment improved cardiac function parameters such as left ventricular developed pressure and coronary flow during reperfusion This compound is widely used in studies investigating MMP activity oxidative stress injury and tissue remodeling
Apexbio Technology LLC o-Phenanthroline 66-71-7 5g
o-Phenanthroline (CAS 66-71-7) is a cell-permeable metal chelator that functions as a non-selective inhibitor of matrix metalloproteinases (MMPs) which are zinc-dependent enzymes implicated in extracellular and intracellular matrix remodeling under stress conditions It has been shown to suppress MMP-2-mediated proteolysis of nuclear lamins in vitro indicating a direct effect on structural nuclear proteins In myocardial ischemia-reperfusion models o-Phenanthroline treatment improved cardiac function parameters such as left ventricular developed pressure and coronary flow during reperfusion This compound is widely used in studies investigating MMP activity oxidative stress injury and tissue remodeling
Chem-Impex International, Inc. Cytosine | 71-30-7 | MFCD00006034 | 5G
Cytosine, 71-30-7, MFCD00006034, 5G
Chem-Impex International, Inc. Cytosine | 71-30-7 | MFCD00006034 | 25G
Cytosine, 71-30-7, MFCD00006034, 25G
Apexbio Technology LLC JNK-IN-7 1408064-71-0 10mg
JNK-IN-7 (CAS 1408064-71-0) is a selective inhibitor targeting c-Jun N-terminal kinases (JNK) exhibiting potent inhibitory activity against JNK1 JNK2 and JNK3 with IC50 values of 1 54 nM 1 99 nM and 0 75 nM respectively Mechanistically JNK-IN-7 blocks phosphorylation of c-Jun a direct downstream substrate of JNK signaling Additionally this compound requires Cys116 in JNK2 for effective inhibition Cellular studies demonstrate that JNK-IN-7 at micromolar concentrations inhibits IRAK1-dependent activation of Pellino an E3 ubiquitin ligase implicated in Toll-like receptor signaling and suppresses c-Jun phosphorylation in RAW264 7 macrophages stimulated by Pam3CSK4 JNK-IN-7 serves as a research tool in studying JNK signaling pathways and innate immune responses