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Br-PEG7-Br is a chemical compound with a molecular weight of 496.23 and a CAS number of 177987-04-1. It is intended for laboratory use and manufacture of substances.
Identified uses include laboratory chemicals and manufacture of substances
High purity of 98.0%
Stable under recommended storage conditions
Colorless to light yellow liquid appearance
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5-Br-CTP is a modified ribonucleoside triphosphate It is designed for use in the generation of RNA libraries via Systematic Evolution of Ligands by EXponential enrichment (SELEX) facilitating the selection of aptamers with enhanced stability Nucleic acids synthesized with 5-Br-CTP display improved resistance to nuclease degradation and increased thermal stability due to bromine substitution at the C-5 position of the cytosine base Based on these properties 5-Br-CTP holds research potential in aptamer selection and nucleic acid-based applications requiring enhanced structural integrity under stringent conditions
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
5-Br-CTP is a modified ribonucleoside triphosphate It is designed for use in the generation of RNA libraries via Systematic Evolution of Ligands by EXponential enrichment (SELEX) facilitating the selection of aptamers with enhanced stability Nucleic acids synthesized with 5-Br-CTP display improved resistance to nuclease degradation and increased thermal stability due to bromine substitution at the C-5 position of the cytosine base Based on these properties 5-Br-CTP holds research potential in aptamer selection and nucleic acid-based applications requiring enhanced structural integrity under stringent conditions
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BR-cpd7 is a PROTAC degrader designed for fibroblast growth factor receptor FGFR1/2, exhibiting a DC50 of 10 nM. This compound has been observed to arrest the cell cycle and inhibit the proliferation of tumor cells that are aberrantly activated by FGFR1/2.
Composed of a ligand for target protein FGFR-IN-12, a linker, and a ligand for E3 ligase Thalidomide-NH-CH2-COOH.
Exhibits antitumor activity.
Arrests cell cycle.
Inhibits proliferation of FGFR1/2 aberrant activated tumor cells.
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BR-cpd7 is a PROTAC degrader designed to target fibroblast growth factor receptor (FGFR1/2). It has a DC50 of 10 nM and works by arresting the cell cycle and inhibiting the proliferation of FGFR1/2 aberrant activated tumor cells.
PROTAC degrader for FGFR1/2
DC50 of 10 nM
Arrests cell cycle
Inhibits proliferation of FGFR1/2 aberrant activated tumor cells
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More