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Ossirene (AS101) is an immunomodulatory tellurium compound used in research as a potent IL-1β inhibitor. It abolishes phosphorylation of STAT3 by inhibiting IL-10 and potently inhibits caspase-1, making it useful for studies of autoimmune disease and certain malignancies.
Potent IL-1β inhibitor.
Inhibits caspase-1.
Abolishes STAT3 phosphorylation via IL-10 inhibition.
Purity ≥98.0%.
Solid, white to off-white appearance.
Molecular weight 312.05 g/mol.
Supplied as 10 mg.
Store at -20°C under nitrogen; in solvent, -80°C (up to 6 months).
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