Organonitrogen Compounds
Medchemexpress LLC Clonidine (hydrochloride) | 4205-91-8 | 99.9% | 1 G
Clonidine hydrochloride is an agonist of α2-adrenoceptor and a potent antihypertensive agent. It has been studied for its various biological activities.
- Induces CGRP (α and β) mRNA expression in endothelial cells
- Increases NO levels in endothelial cells
- Decreases rat body temperature
- Suppresses dopamine efflux in the prefrontal cortex
- Reduces blood pressure
- Enhances RVLM pERK1/2
Medchemexpress LLC Bnc375 | 1557240-80-8 | 99.6% | 394.92 g/mol | C19H23ClN2O3S | 5 MG
BNC375 is a small-molecule, orally available type I positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR). It demonstrates an EC50 of about 1.9 μM and exhibits CNS drug-like properties, supplied as a high-purity research chemical for in vitro and in vivo pharmacology studies.
- Potent, selective type I positive allosteric modulator of α7 nAChR.
- EC50 approximately 1.9 μM in functional assays.
- High purity suitable for in vitro and in vivo studies.
- Soluble in DMSO; recommended in vivo formulations provided.
- Available in milligram-scale quantities for research use.
- Storage recommendations provided to maintain stability.
Sigma Aldrich Fine Chemicals Biosciences Nalpha Tosyl L lysne chlo500MG
Nalpha Tosyl L lysne chlo500MG
eMolecules 134865-70-6 | Medchem Express | 8-M-PDOT | 5mg | 752822498 | HY-101358 | MFCD00901636 | 233.311 | C14H19NO2
ChemScene | (S)-1-(m-Tolyl)ethanamine hydrochloride | 100mg | 632322474 | CS-0153235 | 1630984-18-7 | MFCD11101252 | 171.670 | C9H14ClN
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Medchemexpress LLC Creatine kinase M-type (CKM) protein, human (N-His tag) | 9001-15-4 | >95.0% | 10 UG
Recombinant human creatine kinase M-type (CKM) protein with an N-terminal His tag, expressed in E. coli and supplied as a purified, biologically active enzyme for research use. The protein is approximately 45 kDa, available in microgram quantities, and characterized for activity and purity (>95% by reducing SDS-PAGE). Intended for biochemical assays, enzyme activity studies, and antibody validation; not for clinical or diagnostic use.
- Recombinant human CKM with N-terminal His tag.
- Expressed in E. coli for high-yield production.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Biologically active and suitable for enzymatic assays.
- Supplied in microgram quantities for small-scale experiments.
- Datasheet and COA provided for lot-specific quality information.
Medchemexpress LLC 6-methyl-2-((3-phenoxypropylamino)methyl)quinolin-4(1H)-one | 1434515-70-4 | 99.5% | 322.40 g/mol | C20H22N2O2 | 25MG
UCSF924 is a potent, selective dopamine D4 receptor (DRD4) partial agonist research probe for neuropsychiatric and GPCR pharmacology studies. It exhibits an EC50 of 4.2 nM at DRD4 and shows no significant off-target activity across more than 320 non-olfactory GPCRs. The compound is provided as a solid with high purity suitable for in vitro assays.
- High potency at DRD4 (EC50 4.2 nM).
- Exceptional selectivity versus non-olfactory GPCRs (>320 tested).
- High purity (99.5%).
- Molecular weight 322.40 g/mol and formula C20H22N2O2.
- Available as a solid and as a 10 mM solution in DMSO for convenient use.
- Suitable for cell-based pharmacology and selectivity studies.
eMolecules 108800-18-6 | 1-(3-(BENZYLOXY)PHENYL)GUANIDINE NITRATE | MFCD21364703 | 1g
Ambeed | 5-Cyclopropylpyridin-2-ol | 100mg | 525115768 | A199306 | 1159821-42-7 | MFCD12033218 | 135.166 | C8H9NO
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Medchemexpress LLC 1H-1,2,3-triazole-4-carboxamide derivative (BIIB091) | 2247614-80-6 | 99.9% | C28H34N10O2 | 10MG
BIIB091 is a potent, selective, reversible Bruton's tyrosine kinase (BTK) inhibitor supplied as a high-purity small-molecule reagent for research and preclinical studies. It is used to probe BTK signaling and to evaluate therapeutic approaches in autoimmune and B-cell-mediated disease models. Not for human or clinical use.
- Potent, selective reversible BTK inhibitor (IC50 <0.5 nM).
- High purity (99.85% by HPLC).
- Molecular formula C28H34N10O2; molecular weight 542.64.
- Suitable for in vitro and preclinical assays.
- Orally active profile reported in preclinical studies.
- Supplied as a powder; soluble in DMSO.
eMolecules 71556-70-2 | 1-METHYL-3-(3-OXOCYCLOHEX-1-EN-1-YL)AZEPAN-2-ONE | AstaTech | MFCD18432446 | 221.300 | C13H19NO2 | 95.000 | CN1CCCCC(C2=CC(=O)CCC2)C1=O | 0.25g | 384829410
1-METHYL-3-(3-OXOCYCLOHEX-1-EN-1-YL)AZEPAN-2-ONE | AstaTech | 71556-70-2 | MFCD18432446 | 221.300 | C13H19NO2 | 95.000 | CN1CCCCC(C2=CC(=O)CCC2)C1=O | 0.25g | 384829410
![Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243800.png-250.jpg)
Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 25 MG
Theliatinib is a potent, ATP-competitive, orally active, and highly selective epidermal growth factor receptor (EGFR) inhibitor supplied as a research chemical for biochemical and cellular studies. It shows low-nanomolar potency against wild-type EGFR and measurable activity against clinically relevant mutant forms.
- Potent, ATP-competitive EGFR inhibitor with Ki = 0.05 nM and IC50 = 3 nM.
- Active against EGFR T790M/L858R mutant (IC50 ≈ 22 nM).
- High purity (~99.7%) suitable for biochemical and cellular assays.
- Molecular weight 442.51 g/mol; formula C25H26N6O2.
- Soluble in DMSO and supplied for laboratory research use only.
Medchemexpress LLC HY-19026 5mg Medchemexpress, Siguazodan CAS:115344-47-3 Purity:>98%
Medchemexpress, HY-19026 5mg Siguazodan CAS:115344-47-3 Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 μM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 μM[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1016837-70-9 | Ambeed | 2-(2-Bromophenoxy)-NN-dimethylacetamide | 250mg | 728125864 | A1061323 | MFCD09944437 | 258.115 | C10H12BrNO2
Ambeed | 4-Fluoro-3-((trifluoromethyl)sulfonyl)benzene-1-sulfonyl chloride | 250mg | 570568310 | A187776 | 1027345-07-8 | MFCD16883063 | 326.660 | C7H3ClF4O4S2
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Alkali Scientific Neutral Creatine Sucrose(CSN) Broth 30mL Plate, 10/Pk
Neutral Creatine Sucrose (CSN) medium is a specialized differential medium used primarily in food mycology for the identification and differentiation of Penicillium species. It is particularly valuable in dairy microbiology for distinguishing species associated with cheese production, including Penicillium roqueforti and Penicillium commune. The formulation uses creatine as the primary nitrogen source and sucrose as the carbon source, while bromocresol purple serves as a pH indicator to detect metabolic activity. Organisms capable of strong acid production turn the medium from purple to yellow, whereas weak or non acid producing species leave the medium unchanged. The deep fill plate format provides an optimal environment for fungal growth and diagnostic observation.
eMolecules 1321546-70-6 | Medchem Express | (S)-(-)-5-Fluorowillardiine (hydrochloride) | 10mg | 446267739 | HY-16713A | MFCD28385871 | 253.61 | C7H9ClFN3O4
Medchem Express | Chitinase-IN-1 | 5mg | 446269099 | HY-18598 | 1579991-61-9 | MFCD28385840 | 352.410 | C18H16N4O2S
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Medchemexpress LLC Ripk3-in-1 | 2361139-70-8 | 99.3% | C29H25FN4O4 | 10MG
RIPK3-IN-1 is a small-molecule, type II DFG-out inhibitor of receptor-interacting protein kinase 3 (RIPK3) intended for research use in biochemical and cellular studies. It exhibits potent biochemical activity and is supplied as a high-purity compound suitable for in vitro investigations into necroptosis and related signaling pathways.
- Potent RIPK3 inhibition, IC50 = 9.1 nM.
- High purity, 99.3% by supplier analysis.
- Chemical formula C29H25FN4O4 and molecular weight 512.53 g/mol.
- Suitable for biochemical and cellular assays targeting necroptosis pathways.
- Available in multiple sizes to support assay development and scale-up.