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Theliatinib (HMPL-309) is a highly potent EGFR inhibitor with Ki value of 0 05 nM against the wild type EGFR and IC50 values of 3 nM and 22 nM against EGFR and EGFR T790M/L858R mutant It demonstrats 50 fold greater selectivity for EGFR compared to 72 other kinases
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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