Organooxygen compounds
Medchemexpress LLC 3'-deoxy-3'-fluoroadenosine | 75059-22-2 | MFCD20134043 | 99.3% | 269.24 g·mol⁻¹ | C10H12FN5O3 | 10 MG
3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue used in biochemical and cellular research to probe nucleoside metabolism and antitumor mechanisms. The compound contains a fluorine substituent at the 3' position of adenosine and has activity that can inhibit DNA synthesis and promote apoptosis in model systems.
- High purity, typically 99.3%.
- Chemical formula C10H12FN5O3; molecular weight 269.24 g·mol⁻¹.
- Available as solid powder and as a 10 mM solution in DMSO.
- Pack sizes include small research quantities, for example 10 MG.
- Suitable for studies of DNA synthesis inhibition and apoptotic pathways.
- Datasheets and analytical files (COA, HNMR, LCMS, SDS) available.
Sigma Aldrich Fine Chemicals Biosciences 5 Deoxy 5 methylthoadenos250MG
5 Deoxy 5 methylthoadenos250MG
Medchemexpress LLC 2'-Deoxy-2'-fluoroarabino inosine | 98983-40-5 | C10H11FN4O4 | 5 MG
2'-Deoxy-2'-fluoroarabino inosine is a purine nucleoside analog. These analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms associated with these compounds involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 18-hydroxy-11-deoxy corticosterone | 379-68-0 | 346.46 | C21H30O4 | 1mg
18-Hydroxy-11-deoxy corticosterone (18-OH-DOC) is a mineralocorticoid whose synthesis is regulated by adrenocorticotropic hormone (ACTH) and angiotensin II 18-Hydroxy-11-deoxy corticosterone is an intermediate in the metabolism of progesterone and plays an important role in regulating blood pressure and water-salt balance Continuous infusion of 18-Hydroxy-11-deoxy corticosterone can increase systolic blood pressure in rats and plasma levels of 18-Hydroxy-11-deoxy corticosterone are significantly elevated in the db/db mouse model of type 2 diabetes suggesting its potential involvement in metabolic dysregulation and diabetes-related regulation 18-Hydroxy-11-deoxy corticosterone holds promise for research in areas such as hypertension diabetes and other related fields[1]
Medchemexpress LLC 2'-Deoxy-5,N4-dimethylcytidine | 25406-44-4 | 97.5% | 255.27 | C11H17N3O4 | 10 MG
2'-Deoxy-5,N4-dimethylcytidine is a purine nucleoside analog provided as an off-white to light yellow solid for laboratory research. It is used as a biochemical reagent in studies of DNA synthesis and apoptosis and is supplied at high reported purity. Handle and store according to supplier recommendations for frozen storage when required.
- High purity suitable for research applications.
- Off-white to light yellow solid form for easy handling.
- Multiple small package sizes available for flexibility.
- Stable when stored at -20°C in powder form.
- Useful as a biochemical reagent in nucleoside and antitumor studies.
Medchemexpress LLC 5'-Deoxy-5-fluorocytidine | 66335-38-4 | 99.9% | 245.21 | 25 G
5'-Deoxy-5-fluorocytidine is a cytidine analog and a metabolite of Capecitabine. It undergoes enzymatic conversions in the body, ultimately producing 5-fluorouracil, which exerts anti-tumor effects. This compound is used in research for various solid tumors.
- Cytidine analog
- Metabolite of Capecitabine
- Converted to 5-fluorouracil for anti-tumor effects
- Utilized in research for solid tumors, including colorectal cancer, non-small cell lung cancer, and breast cancer
- Inhibits proliferation of chemotherapy-resistant A549 paraclone cells in vitro
Cayman Chemical 4-deoxy-4a-Phorbol 10mg
A tetracyclic diterpene found in croton oil; has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4a-phorbol esters
Medchemexpress LLC 9-(2-deoxy-beta-D-ribofuranosyl)-6-methylpurine | 16006-64-7 | MFCD29059892 | 95.0% | 249.27 g·mol^-1 | C12H15N3O3 | 10 MG
9-(2-Deoxy-beta-D-ribofuranosyl)-6-methylpurine is a deoxyribonucleoside derivative of 6-methylpurine supplied as an off-white to light yellow powder for research use in biochemical and medicinal chemistry applications. The product is provided with analytical documentation and recommended cold-storage conditions.
- Purity 95.0%.
- CAS number 16006-64-7.
- Molecular weight 249.27 g·mol^-1.
- Supplied as an off-white to light yellow powder.
- Recommended storage: powder at -20°C for long-term storage; in solvent at -80°C for extended stability.
- Documentation available: data sheet, certificate of analysis, and safety data sheet.
Cayman Chemical 2-deoxy-D-Glucose-13C6 10mg
An internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS
Medchemexpress LLC 2′-deoxy-β-L-uridine | 31501-19-6 | MFCD02262147 | 100.0% | 227.195 g·mol^-1 | C9H11N2O5 | 500 MG
2′-Deoxy-β-L-uridine is a nucleoside analogue for biochemical and antiviral research. It functions as a substrate for certain viral enzymes and, through its 5'-triphosphates, interacts with viral DNA polymerase, making it useful for enzymatic and polymerase assays. The compound is provided as a high-purity research chemical.
- Nucleoside analogue for biochemical and antiviral research.
- Specific substrate for viral enzymes and polymerase assay applications.
- High reported purity: 99.96%.
- Chemical formula C9H11N2O5; molecular weight 227.195 g·mol^-1.
- Available in research-scale quantities (500 mg).
Medchemexpress LLC 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) | 153666-19-4 | 99.9% | C9H16O9 | 50 MG
3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a type of sialic acid. It can be hydrolyzed by sialidase from the loach (Misgurnus fossilis). This product is supplied as a white to off-white solid.
- High purity: 99.90%
- Molecular weight: 268.22
- Solubility in water: 100 mg/mL
- Stable as powder at -20°C for 3 years, 4°C for 2 years
- Stable in solvent at -80°C for 6 months, -20°C for 1 month
Sigma Aldrich Fine Chemicals Biosciences 2-Deoxy-D-ribose 97% | 533-67-5 | MFCD00135904 | 5G
2-Deoxy-D-ribose 97% | Purity: 97% | Mol Wt: 134.13 | 533-67-5 | MFCD00135904 | 5G
Chem-Impex International, Inc. 2-Fluoro-2-deoxy-D-glucose | MFCD00077527 | 100MG
2-Fluoro-2-deoxy-D-glucose, MFCD00077527, 100MG
Medchemexpress LLC 1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine | 16053-52-4 | C10H14N2O5 | 25 MG
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analog with a purity of 99.68% and a molecular weight of 242.23. This compound exhibits insertional activity towards replicated DNA, making it suitable for labeling cells and tracking DNA synthesis. It also demonstrates antiviral activity against HBV in human 2.2.15 cells with an EC50 of 10 μg/mL and against DHBV in duck hepatocytes with an EC50 of 4.13 μM. Cytotoxicity against human HuH7 cells is observed with a CC50 of > 200 μg/mL.
- Thymidine analog
- Exhibits insertional activity towards replicated DNA
- Used for labeling cells and tracking DNA synthesis
- Demonstrates antiviral activity against HBV and DHBV
- High purity of 99.68%
- Appears as a white to off-white solid
Selleck Chemical LLC 2-Deoxy-D-ribose S3101-100mg
2-Deoxy-D-ribose (Thyminose Deoxyribose) is an endogenous metabolite