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An organic polysulfide compound found in garlic that acts as an H2S donor; reduces the survival of prostate cancer PC-3 cells (IC50 = 22 μM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 μM); suppresses the growth of PC-3 xenografts in vivo in mice and induces vascular smooth muscle relaxation.
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Diallyl trisulfide (CAS 2050-87-5) is an organosulfur compound derived from garlic, supplied as a purified solid for laboratory research. It is used to investigate apoptosis, anticancer activity, and related cellular signaling pathways.
High purity suitable for analytical and biological studies.
Chemical formula C6H10S3; molecular weight 178.34 g/mol.
Reported bioactivities include anticancer, anti-inflammatory, antioxidant, and antibacterial effects.
Suitable for in vitro and biochemical research (research use only).
Available in small-mass packs convenient for bench-scale experiments.
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An organic polysulfide compound found in garlic that acts as an H2S donor; reduces the survival of prostate cancer PC-3 cells (IC50 = 22 μM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 μM); suppresses the growth of PC-3 xenografts in vivo in mice and induces vascular smooth muscle relaxation.
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Dimethyl trisulfide (DMTS) a volatile sulfur compound (VSC) is a major aroma consituent in cooked Brassicaceous vegetables. Dimethyl trisulfide formation is reported during beer aging. It has been reported to be responsible for common malodour from fungating cancer samples. It is an important taste and odor (TO)-causing compound in China mainly associated with the septic/swampy odor. It has been identified as a common odor-producing compound by Microcystis (on its decay). Granular activated carbon (GAC) adsorption of dimethyl trisulfide an algal odorant has been reported.
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An organic polysulfide compound found in garlic that acts as an H2S donor; reduces the survival of prostate cancer PC-3 cells (IC50 = 22 μM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 μM); suppresses the growth of PC-3 xenografts in vivo in mice and induces vascular smooth muscle relaxation.
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Chemical. CAS 1143863-69-7. Formula C15H11FO2. MW 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.
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Dimethyl trisulfide (CAS 3658-80-8) is a small-molecule organosulfur compound investigated for its ability to modulate cellular signaling pathways and enzyme activities Studies indicate that it can inhibit specific intracellular signaling cascades resulting in altered regulation of cellular biological functions Due to its bioactivity dimethyl trisulfide serves as a valuable tool for elucidating disease mechanisms involving the affected pathways and for evaluating potential therapeutic strategies in biomedical research
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NX-2127 is a unique potent inhibitor of BTK that prevents its functions by catalyzing the ubiquitylation and proteasomal degradation of BTK rather than via direct binding NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells
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