Phenylpropanoids and polyketides
Medchemexpress LLC Apigenin-7-glucuronide | 29741-09-1 | 446.36 | 1 ML
Apigenin-7-glucuronide is a chemical compound that acts as an inhibitor of Matrix Metalloproteinases (MMP) activities, with specific IC50 values for MMP-3, MMP-8, MMP-9, and MMP-13. This product is intended for research use only.
- Inhibits Matrix Metalloproteinases (MMP) activities
- Purity of 99.74%
- Available as a solid
- Soluble in DMSO for in vitro studies
- Specific storage conditions for powder and in solvent
Medchemexpress LLC Apigenin-7-glucuronide | 29741-09-1 | 446.36 | 1 MG
Apigenin-7-glucuronide is a compound that inhibits Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, and 0.27 μM for MMP-3, MMP-8, MMP-9, and MMP-13, respectively. This product is for research use only.
- Inhibits matrix metalloproteinases (MMPs)
- Effective against MMP-3, MMP-8, MMP-9, and MMP-13
- Soluble in DMSO up to 250 mg/mL
Medchemexpress LLC Apigenin 7-O-glucuronide | 29741-09-1 | MFCD23699539 | >95.0% | 10 MG
Apigenin 7-O-glucuronide is a flavonoid glucuronide supplied as an analytical standard for research and analytical applications. It has reported inhibitory activity against matrix metalloproteinases, with IC50s of 12.87 μM (MMP-3), 22.39 μM (MMP-8), 17.52 μM (MMP-9), and 0.27 μM (MMP-13). CAS: 29741-09-1; molecular weight: 446.36 g/mol.
- Provided as a 10 mg analytical standard for research use only.
- Reported inhibitory activity against multiple MMP enzymes with published IC50 values.
- Chemical formula C21H18O11 and molecular weight 446.36 g/mol.
- Commonly used in biochemical and analytical assays to characterize apigenin metabolites.
Apexbio Technology LLC AKT inhibitor VIII(Synonyms: AKTi-1/2, Akt Inhibitor VIII, AKTi VIII, Akt kinase inhibitor VIII, Isozyme-selective AKT inhibitor VIII), 10mM (in 1mL DMSO), CAS: 612847-09-3.
AKT inhibitor VIII (CAS 612847-09-3) is a cell-permeable reversible inhibitor targeting Akt isoforms Akt1 Akt2 and Akt3 exhibiting IC50 values of 58 nM 210 nM and 2119 nM respectively It acts by suppressing Akt signaling as demonstrated by its ability to inhibit IGF-1-stimulated Akt phosphorylation and to reduce PRAS40 phosphorylation in PC12 cells In MCF-7 breast cancer cells AKT inhibitor VIII enhances the antiproliferative activity of furanodiene augmenting its effects on Akt/p-Akt downregulation and promoting PARP cleavage This compound is valuable for exploring Akt-dependent signaling pathways in oncology research and neuronal cell biology studies