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Phenylpropanoids and polyketides

Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
Macrolides and analogues (3)
Cinnamic acids and derivatives (2)
Coumarins and derivatives (2)

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1

7-(Diethylamino)-3-(2-thienyl)coumarin 98.0+%, TCI America™

CAS: 117850-52-9 Molecular Formula: C17H17NO2S Molecular Weight (g/mol): 299.39 MDL Number: MFCD29089355 InChI Key: ALJRTBKJTPXLCD-UHFFFAOYSA-N PubChem CID: 57494118 IUPAC Name: 7-(diethylamino)-3-(thiophen-2-yl)-2H-chromen-2-one SMILES: CCN(CC)C1=CC=C2C=C(C3=CC=CS3)C(=O)OC2=C1

PubChem CID 57494118
CAS 117850-52-9
Molecular Weight (g/mol) 299.39
MDL Number MFCD29089355
SMILES CCN(CC)C1=CC=C2C=C(C3=CC=CS3)C(=O)OC2=C1
IUPAC Name 7-(diethylamino)-3-(thiophen-2-yl)-2H-chromen-2-one
InChI Key ALJRTBKJTPXLCD-UHFFFAOYSA-N
Molecular Formula C17H17NO2S
2

Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | >98.0% | C19H20O2 | 10MG
SDP

(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (CAS 100667-52-5) is a diarylheptanoid research chemical used as a biochemical reagent for laboratory studies. It appears as a white to off-white solid and is characterized by molecular formula C19H20O2 and a molecular weight of 280.4 g/mol. The compound is provided in small research-scale quantities for analytical, assay, and synthetic applications.

  • High purity (>98.0%).
  • Accurate molecular formula C19H20O2.
  • Suitable for assay and analytical use in research settings.
  • Supplied in small milligram package sizes for laboratory workflows.
  • Includes standard structural identifiers for cheminformatics (SMILES, InChIKey).

ENCOMPASS_PREFERRED
3

Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | 97.0% | 280.36 g/mol | C19H20O2 | 5 MG
SDP

(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one is a diarylheptanoid small-molecule for laboratory research and analytical applications. The compound is supplied as a solid with molecular formula C19H20O2, molecular weight 280.36 g/mol, and an analytical purity of 97.0% (NMR). Store protected from light at low temperatures; consult the certificate of analysis for batch-specific handling and stability information.

  • Solid, white to off-white appearance.
  • Molecular formula C19H20O2.
  • Molecular weight 280.36 g/mol.
  • Analytical purity 97.0% (NMR).
  • Storage: keep container tightly sealed, protect from light; recommended -20°C for solid, in solvent -80°C for 6 months or -20°C for 1 month.
  • Intended for research and analytical use only; not for human therapeutic use.

ENCOMPASS_PREFERRED
4

Medchemexpress LLC 5Z-7-oxozeaenol | 253863-19-3 | MFCD12912700 | 99.6% | 362.37 g/mol | C19H22O7 | 5 MG
SDP

5Z-7-Oxozeaenol is a natural, fungal-derived small molecule that acts as a potent, irreversible, and selective inhibitor of TAK1 and VEGF-R2. It is used in biochemical and cellular research to probe TAK1- and VEGFR2-mediated signaling; reported IC50 values are 8 nM for TAK1 and 52 nM for VEGF-R2. The compound is supplied as a solid with high purity suitable for research applications.

  • Potent, irreversible inhibition of TAK1 (IC50 = 8 nM).
  • Selective activity against VEGF-R2 (IC50 = 52 nM).
  • High purity suitable for biochemical and cellular assays.
  • Solid form convenient for handling and storage.
  • Useful for studying MAPKKK-mediated signaling pathways.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC 5Z-7-Oxozeaenol | 253863-19-3 | 99.3% | 10 MG
SDP

5Z-7-Oxozeaenol is a natural anti-protozoan compound of fungal origin, serving as a potent, irreversible, and selective inhibitor of TAK1 and VEGF-R2, with IC50 values of 8 nM and 52 nM, respectively.

  • Potent, irreversible, and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 (TAK1, IC50: 8.1 nM).
  • Less active on MEK1 (IC50: 411 nM).
  • Prevents inflammation by inhibiting TAK1 MAPK kinase kinase catalytic activity.
  • Inhibitor of VEGF-R2 (IC50: 52 nM).
  • Also inhibits VEGF-R3 (IC50: 110 nM), FLT3 (IC50: 170 nM), PDGFR-β (IC50: 340 nM), B-RAF VE (IC50: 6300 nM), and SRC (IC50: 6600 nM).
  • Inhibits JNK/p38 pathway (signal-specific, not a direct inhibitor).
  • Suppresses PMA-induced AP-1 activity in KT cells; no effect on IL-1-induced NF-kB activity in KK cells.

ENCOMPASS_PREFERRED
6

Medchemexpress LLC 5Z-7-Oxozeaenol | 253863-19-3 | 99.3% | 25 MG
SDP

5Z-7-Oxozeaenol is a natural anti-protozoan compound of fungal origin. It acts as a potent, irreversible, and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively. This product is for research use only.

  • Potent and selective inhibitor of TAK1 (IC50 8.1 nM).
  • Inhibits VEGF-R2, VEGF-R3, FLT3, PDGFR-β, B-RAF VE, and SRC.
  • Prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase.
  • Inhibits JNK/p38 pathway in a signal-specific manner.
  • Exhibits antiproliferative and cytotoxic activities against various cell lines.

ENCOMPASS_PREFERRED