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Phenylpropanoids and polyketides

Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
Coumarins and derivatives (2)
Flavonoids (2)
Depsides and depsidones (1)

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1

4-Methylcoumarin 98.0+%, TCI America™

CAS: 607-71-6 Molecular Formula: C10H8O2 Molecular Weight (g/mol): 160.172 MDL Number: MFCD00185474 InChI Key: PSGQCCSGKGJLRL-UHFFFAOYSA-N PubChem CID: 11833 IUPAC Name: 4-methylchromen-2-one SMILES: CC1=CC(=O)OC2=CC=CC=C12

PubChem CID 11833
CAS 607-71-6
Molecular Weight (g/mol) 160.172
MDL Number MFCD00185474
SMILES CC1=CC(=O)OC2=CC=CC=C12
IUPAC Name 4-methylchromen-2-one
InChI Key PSGQCCSGKGJLRL-UHFFFAOYSA-N
Molecular Formula C10H8O2
2

8-Methoxy-4-methylbenzo[g]coumarin 98.0+%, TCI America™

CAS: 69169-71-7 Molecular Formula: C15H12O3 Molecular Weight (g/mol): 240.26 MDL Number: MFCD00445784 InChI Key: GWFUYESISQUIHB-UHFFFAOYSA-N Synonym: 8-Methoxy-4-methyl-2H-naphtho[2,3-b]pyran-2-one PubChem CID: 12448345 IUPAC Name: 8-methoxy-4-methyl-2H-benzo[g]chromen-2-one SMILES: COC1=CC=C2C=C3C(C)=CC(=O)OC3=CC2=C1

PubChem CID 12448345
CAS 69169-71-7
Molecular Weight (g/mol) 240.26
MDL Number MFCD00445784
SMILES COC1=CC=C2C=C3C(C)=CC(=O)OC3=CC2=C1
Synonym 8-Methoxy-4-methyl-2H-naphtho[2,3-b]pyran-2-one
IUPAC Name 8-methoxy-4-methyl-2H-benzo[g]chromen-2-one
InChI Key GWFUYESISQUIHB-UHFFFAOYSA-N
Molecular Formula C15H12O3
3

eMolecules​ AstaTech / BENZYL 3-(BENZOYLOXY)-4-OXOPIPERIDINE-1-CARBOXYLATE / 0.1g / 718060540 / W11413 / 95.000 / 1431285-71-0 / MFCD28991976 / 353.374 / C20H19NO5

AstaTech / BENZYL 3-(BENZOYLOXY)-4-OXOPIPERIDINE-1-CARBOXYLATE / 0.1g / 718060540 / W11413 / 95.000 / 1431285-71-0 / MFCD28991976 / 353.374 / C20H19NO5

ENCOMPASS_PREFERRED
4

Medchemexpress LLC Apigenin (4',5,7-Trihydroxyflavone) | 520-36-5 | HY-N1201 | 98.9% | 270.24 | 500 MG
SDP

Apigenin (4',5,7-Trihydroxyflavone) is identified as a competitive CYP2C9 inhibitor with a Ki of 2 μM. It demonstrates the ability to inhibit cell proliferation, with growth inhibition rates of 38%, 71%, and 99% at concentrations of 20, 40, and 80 μM respectively. The compound also suppresses clone formation in SGC-7901 cells in a dose- and time-dependent manner.

  • Competitive inhibitor of Cytochrome P450 2C9 (CYP2C9).
  • Exhibits cell proliferation inhibitory activity.
  • Suppresses clone formation in specific cell lines.

ENCOMPASS_PREFERRED
5

Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 1 G
SDP

Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor that inhibits cytochrome P450 2C9 in a purified enzyme system. It demonstrates dose- and time-dependent inhibition of cell proliferation in SGC-7901 cells.

  • Competitive CYP2C9 inhibitor with a Ki of 2 μM.
  • Inhibits cytochrome P450 2C9 in a purified, reconstituted enzyme system.
  • Demonstrates inhibition of cell proliferation in SGC-7901 cells in a dose- and time-dependent manner.
  • Achieves growth inhibition rates of 38%, 71%, and 99% at 20, 40, and 80 μM, respectively, on the 7th day.
  • Cloning efficiency in SGC-7901 cells treated with 80 μM for 24 and 48 hours was 9.8% and 5%, respectively.

ENCOMPASS_PREFERRED