Amylin, amide, human is a 37-amino acid polypeptide and a pancreatic hormone cosecreted with insulin. It plays unique roles in metabolism and glucose homeostasis, inhibiting glucagon secretion, delaying gastric emptying, and acting as a satiety agent. This product is for research use only and not sold to patients.
- Inhibits glucagon secretion
- Delays gastric emptying
- Acts as a satiety agent
- Stimulates human amylin receptor CTR1 and CTR2 in MCF-7 cells
- Results in cAMP production with an EC50 of 35.2±7.5 nM in MCF-7 cells
- Subcutaneous injection in Swiss male mice showed a half-time of 23 min