Dexmedetomidine is a potent, selective, and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. It shows 1620-fold selectivity against α1-adrenoceptor and exhibits anxiolysis, sedation, and modest analgesia effects.
- Potent α2-adrenoceptor agonist
- Selective α2-adrenoceptor agonist
- Orally active
- Exhibits anxiolysis
- Provides sedation
- Offers modest analgesia effects