Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent and BBB-permeable cholinergic agonist. It modulates the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) and inhibits p53 mutant peptide aggregation in vitro. Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development, and deuteration has the potential to affect pharmacokinetic and metabolic profiles.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Modulates dopaminergic neuron activity
- Inhibits p53 mutant peptide aggregation in vitro
- Deuterium labeled for potential pharmacokinetic and metabolic profile effects