Lactic Acid
Sigma Aldrich DL-Indole-3-lactic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich DL-Lactic acid
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Propanoic acid, 2-hydroxy-, sodium salt (1:1) | 72-17-3 | 98.0% | 2 ML
Lactic acid sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator. It induces lysine residues lactylation, functions as an oncometabolite, and has an immune protective role in anti-tumor immunity. It also exhibits antimicrobial activity and can be used as a food preservative.
- Significantly decreases cell proliferation and migration at 20 mM concentration
- Switches cell metabolism towards oxidative phosphorylation
- Increases protein and mRNA expression levels of MCT1 and HCAR1
- Demonstrates CD8+ T cell-dependent tumor growth inhibition in MC38 colon cancer model
Medchemexpress LLC Propanoic acid, 2-hydroxy-, sodium salt (1:1) | 72-17-3 | 60.0% | 1 ML
Lactic acid sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. It is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. As an oncometabolite, it plays an immune protective role in anti-tumor immunity. It also possesses antimicrobial activity and can be utilized as a food preservative. This product is a 60% (w/w) solution in water, with 1 mL containing 798 mg of Lactic acid sodium at a concentration of 7.12 M.
- Decreases cell proliferation and migration.
- Switches cell metabolism towards oxidative phosphorylation.
- Increases protein and mRNA expression levels of MCT1 and HCAR1.
Medchemexpress LLC Propanoic acid, 2-hydroxy-, calcium salt (2:1) | 814-80-2 | 98.5% | 500 MG
Lactic acid calcium (DL-Lactic acid calcium) is an HCAR1 activator and an epigenetic modulator that induces lysine residues lactylation. It is a glycolysis end-product that bridges glycolysis and oxidative phosphorylation. Acting as an oncometabolite, it plays an immune protective role in anti-tumor immunity, possesses antimicrobial activity, and can be used as a food preservative.
- Activates HCAR1 and induces lysine residues lactylation.
- Bridges glycolysis and oxidative phosphorylation.
- Acts as an oncometabolite with immune protective role in anti-tumor immunity.
- Possesses antimicrobial activity.
- Can be used as a food preservative.
- Significantly decreases cell proliferation and migration in vitro.
- Increases protein and mRNA expression levels of MCT1 and HCAR1.
- Suppresses tumor growth in vivo.