Prasugrel hydrochloride is a thienopyridine and proagent that inhibits platelet function. It is an orally active and potent P2Y12 receptor antagonist, inhibiting ADP-induced platelet aggregation. As an inactive prodrug, it requires metabolic processing to generate its active antiplatelet metabolite, which is rapidly absorbed from the gut.
- Thienopyridine and proagent
- Inhibits platelet function
- Orally active and potent P2Y12 receptor antagonist
- Inhibits ADP-induced platelet aggregation
- Acts faster and is significantly more potent than clopidogrel in vivo
- Requires metabolic processing to generate active antiplatelet metabolite
- Rapidly absorbed from the gut
- Maximum plasma levels of active metabolite achieved within 1 hour
- Effective, maximum inhibition of platelet aggregation at 1-2 hours