Trifluoroacetic Acid
Medchemexpress LLC CH-0793076 TFA (TP3076 TFA) | 2740278-76-4 | 98.7% | 572.53 g·mol⁻¹ | C28H27F3N4O6 | 5 MG
CH-0793076 TFA is a camptothecin-like hexacyclic analog and the active metabolite of TP300 that functions as a DNA topoisomerase I inhibitor. It is supplied as a trifluoroacetate salt for research use and has demonstrated antiproliferative activity, including activity against cells expressing BCRP.
- Inhibits DNA topoisomerase I (reported IC50 ≈ 2.3 μM).
- Active metabolite of TP300.
- Demonstrates antiproliferative activity in cellular assays.
- Provided as a trifluoroacetate salt suitable for biochemical studies.
- Molecular weight 572.53 g·mol⁻¹; chemical formula C28H27F3N4O6.
Medchemexpress LLC Homoglutathione trifluoroacetate | 435.37 | C13H20F3N3O8S | 25mg
Homoglutathione (TFA) is a biological molecule
eMolecules Trifluoroacetic acid, peptide synthesis grade | Oakwood Chemical | 76-05-1 | MFCD00004169 | 114.023 | C2HF3O2 | 99.000 | OC(=O)C(F)(F)F | 100ml | 537677722
Trifluoroacetic acid, peptide synthesis grade | Oakwood Chemical | 76-05-1 | MFCD00004169 | 114.023 | C2HF3O2 | 99.000 | OC(=O)C(F)(F)F | 100ml | 537677722
Medchemexpress LLC Mi-1061 Tfa | 1410737-35-7 | 97.5% | 696.47 | C32H27Cl2F4N3O6 | 25MG
MI-1061 TFA is the trifluoroacetate (TFA) salt of MI-1061, a potent, orally bioavailable inhibitor of the MDM2-p53 protein-protein interaction. It activates p53, induces apoptosis in tumor models, and shows selective activity in p53 wild-type cell lines.
- Potent biochemical MDM2-p53 interaction inhibitor (IC50 = 4.4 nM; Ki = 0.16 nM).
- Selective cellular activity with IC50 = 100 nM in SJSA-1 and 250 nM in HCT-116 p53+/+; >10,000 nM in p53-/- cells.
- Trifluoroacetate salt presented as a solid form.
- Molecular weight 696.47 and molecular formula C32H27Cl2F4N3O6.
- Intended for research use as a tool compound to study p53 activation and antitumor effects.
- Purity listed as 97.47%.