Acyl bromides
Medchemexpress LLC N4-Benzoyl-2 -O-meth 250mg
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Medchemexpress LLC N-Benzoyl-(2R,3S)-3-phenylisoserine | 132201-33-3 | 50 MG
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain, crucial for the strong antitumor activity of Taxol. It has a molecular weight of 285.29, a chemical formula of C16H15NO4, and appears as a white to off-white solid with 99.48% purity.
- Crucial for the strong antitumor activity of Taxol
- Exhibits cellular effects, showing 62% inhibition in B16 melanoma cells at 42 μM
- Has an IC50 of > 100 μM in rat L6 cells after 70 hours
- White to off-white solid appearance
- Purity of 99.48%
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 25 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, particularly against indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Roslin 2 bromide | 29574-21-8 | 99.0% | C13H19BrN4 | 1 MG
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that exhibits anticancer effects. It functions by binding to FAK, thereby disrupting the interaction between FAK and p53.
- Decreases cancer cell viability and clonogenicity in a p53-dependent manner.
- Increases p53 transcriptional activity, which is inhibited by FAK, using p21, Mdm-2, and Bax-promoter targets.
- Leads to increased expression of p53 targets: p21, Mdm-2, and Bax proteins.
- Significantly reduces tumor growth, disrupts the FAK and p53 complex, and up-regulates p21 in HCT116 p53+/+ xenografts (not in HCT116 p53-/- xenografts).