Acyl bromides
![Sigma Aldrich 3-[1-(Dimethylamino)ethyl]phenol](https://assets.fishersci.com/TFS-Assets/CCG/Sigma-Aldrich/product-images/5a65fe05-c007-4659-8a13-435e3940cc83.jpg-250.jpg)
Sigma Aldrich 3-[1-(Dimethylamino)ethyl]phenol
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Propionyl Bromide 98.0+%, TCI America™
CAS: 598-22-1 Molecular Formula: C3H5BrO Molecular Weight (g/mol): 136.976 MDL Number: MFCD00000116 InChI Key: RIBFXMJCUYXJDZ-UHFFFAOYSA-N Synonym: propionyl bromide,propanoyl-bromide,propionylbromide,propanyl bromide,acmc-209mg3,ksc270q9p,ribfxmjcuyxjdz-uhfffaoysa,inchi=1/c3h5bro/c1-2-3 4 5/h2h2,1h3 PubChem CID: 69018 IUPAC Name: propanoyl bromide SMILES: CCC(=O)Br
2-Bromoisobutyryl Bromide 98.0+%, TCI America™
CAS: 20769-85-1 Molecular Formula: C4H6Br2O Molecular Weight (g/mol): 229.899 MDL Number: MFCD00000122 InChI Key: YOCIJWAHRAJQFT-UHFFFAOYSA-N Synonym: 2-bromo-2-methylpropionyl bromide,2-bromoisobutyryl bromide,propanoyl bromide, 2-bromo-2-methyl,bibb,2-bromo-2-methylpropionylbromide,unii-627f9n9dya,2-bromoisobutyrylbromide,2-bromo-2-methyl-propionyl bromide,alpha-bromoisobutyryl bromide,2-bromo-2-methyl-propanoyl bromide PubChem CID: 88685 IUPAC Name: 2-bromo-2-methylpropanoyl bromide SMILES: CC(C)(C(=O)Br)Br
2-Acetoxyisobutyryl bromide, 96%
CAS: 40635-67-4 Molecular Formula: C6H9BrO3 Molecular Weight (g/mol): 209.039 MDL Number: MFCD00040923 InChI Key: OOKAXSHFTDPZHP-UHFFFAOYSA-N Synonym: 2-acetoxyisobutyryl bromide,2-acetoxy-2-methylpropionyl bromide,1-bromocarbonyl-1-methylethyl acetate,alpha-acetoxy-isobutyryl bromide,a-acetoxyisobutyryl bromide,alpha-acetoxyisobutyryl bromide,2-acetoxyisobutyryl bromide;2-acetoxy-2-methylpropionyl bromide,propanoyl bromide, 2-acetyloxy-2-methyl,aibb,pubchem17437 PubChem CID: 2724715 IUPAC Name: (1-bromo-2-methyl-1-oxopropan-2-yl) acetate SMILES: CC(=O)OC(C)(C)C(=O)Br
Propionyl bromide, 95%
CAS: 598-22-1 Molecular Formula: C3H5BrO Molecular Weight (g/mol): 136.98 MDL Number: MFCD00000116 InChI Key: RIBFXMJCUYXJDZ-UHFFFAOYSA-N Synonym: propionyl bromide,propanoyl-bromide,propionylbromide,propanyl bromide,acmc-209mg3,ksc270q9p,ribfxmjcuyxjdz-uhfffaoysa,inchi=1/c3h5bro/c1-2-3 4 5/h2h2,1h3 PubChem CID: 69018 IUPAC Name: propanoyl bromide SMILES: CCC(=O)Br
2-Bromoisobutyryl bromide, 97%
CAS: 20769-85-1 Molecular Formula: C4H6Br2O Molecular Weight (g/mol): 229.899 MDL Number: MFCD00000122 InChI Key: YOCIJWAHRAJQFT-UHFFFAOYSA-N Synonym: 2-bromo-2-methylpropionyl bromide,2-bromoisobutyryl bromide,propanoyl bromide, 2-bromo-2-methyl,bibb,2-bromo-2-methylpropionylbromide,unii-627f9n9dya,2-bromoisobutyrylbromide,2-bromo-2-methyl-propionyl bromide,alpha-bromoisobutyryl bromide,2-bromo-2-methyl-propanoyl bromide PubChem CID: 88685 IUPAC Name: 2-bromo-2-methylpropanoyl bromide SMILES: CC(C)(C(=O)Br)Br
2-Bromo-2-methylpropionyl Bromide, 98%
CAS: 20769-85-1 Molecular Formula: C4H6Br2O Molecular Weight (g/mol): 229.9 MDL Number: MFCD00000122 InChI Key: YOCIJWAHRAJQFT-UHFFFAOYSA-N Synonym: 2-bromo-2-methylpropionyl bromide,2-bromoisobutyryl bromide,propanoyl bromide, 2-bromo-2-methyl,bibb,2-bromo-2-methylpropionylbromide,unii-627f9n9dya,2-bromoisobutyrylbromide,2-bromo-2-methyl-propionyl bromide,alpha-bromoisobutyryl bromide,2-bromo-2-methyl-propanoyl bromide PubChem CID: 88685 IUPAC Name: 2-bromo-2-methylpropanoyl bromide SMILES: CC(C)(C(=O)Br)Br
Medchemexpress LLC Aclidinium Bromide | 320345-99-1 | 98.96% | C26H30BrNO4S2 | 1 ML
Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research into chronic obstructive pulmonary disease (COPD). It has shown potent antagonism of human muscarinic receptors preclinically, with a long residence time at M3 receptors, suggesting potential for sustained bronchodilation. Early clinical studies have indicated low systemic bioavailability and a favorable safety profile.
- Long-acting muscarinic antagonist
- Potential for chronic obstructive pulmonary disease (COPD) research
- Exhibits potent antagonism of human muscarinic receptors
- Long residence time at M3 receptors for sustained bronchodilation
- Low systemic bioavailability
- Favorable safety profile
- Rapidly hydrolyzed in human plasma
![Medchemexpress LLC 1-Hexadecanaminium, N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-, bromide (1:1) | 553-08-2 | 99.9% | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000412988-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Hexadecanaminium, N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-, bromide (1:1) | 553-08-2 | 99.9% | 100 MG
Thonzonium bromide is an antibacterial agent and a monocationic surface-active agent. It inhibits RANKL-induced osteoclast formation and bone resorption in vitro, and prevents LPS-induced bone loss in vivo. This compound also inhibits proton transport in a dose-dependent manner (EC50=69 μM).
- Antibacterial agent.
- Monocationic surface-active agent.
- Inhibits RANKL-induced osteoclast formation and bone resorption in vitro.
- Prevents LPS-induced bone loss in vivo.
- Inhibits proton transport in a dose-dependent manner (EC50=69 μM).
- Blocks RANKL-induced activation of NF-κB, ERK, and c-Fos, as well as NFATc1 induction.
- Disrupts F-actin ring formation, causing disturbances in cytoskeletal structure in mature osteoclasts during bone resorption.
- Exhibits protective effects in an in vivo murine model of LPS-induced calvarial osteolysis.
![Medchemexpress LLC Piperidinium, 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethyl-, bromide (1:1) | 76-90-4 | 99.9% | 420.34 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387143-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Piperidinium, 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethyl-, bromide (1:1) | 76-90-4 | 99.9% | 420.34 | 1 ML
Mepenzolate bromide is an orally administered muscarinic receptor antagonist, with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome, and is also identified as a GPR109A inhibitor.
- Orally administered muscarinic receptor antagonist
- Suppresses gastrointestinal hypermotility
- Effective against irritable bowel syndrome
- Functions as a GPR109A inhibitor
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 5mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 100mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 50mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 10mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism