Alkyl fluorides
Medchemexpress LLC Lmp2a (426-434) | 152274-91-4 | 96.1% | 906.16 | 5 MG
LMP2A (426-434) is a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). It can trigger an immune response in individuals expressing different HLA-A*02 subtypes (A*02:01, A*02:03, A*02:06, and A*02:07). This peptide induces a strong IFN-γ secretion response, stimulating the production of a high proportion of CD8+ IFN-γ+ T cells. It also induces specific CTLs to effectively kill target cells expressing LMP2A. It is used in the study of EBV-related malignant tumors such as Hodgkin's disease and nasopharyngeal carcinoma.
- Induces IFN-γ secreting cells at a frequency of 80.6 SFC/5x10⁴ CD8+ T cells (at 20 μg/mL for 24 h).
- Significantly increases the proportion of CD8+IFN-γ+ cells (at 20 μg/mL for 2 weeks).
- Specific CTLs effectively kill peptide-pulsed T2 cells and 293T-LMP2A cells (at 20 μg/mL for 4 h).
Medchemexpress LLC LMP2A (426-434) | 152274-91-4 | 96.1% | 906.16 | 25 MG
LMP2A (426-434) is an HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). It can trigger an immune response in individuals expressing various HLA-A*02 subtypes and induces a strong IFN-γ secretion response, leading to a high proportion of CD8+ IFN-γ+ T cells. It induces specific CTLs that effectively kill target cells expressing LMP2A.
- Suitable for studying EBV-related malignant tumors, such as Hodgkin's disease and nasopharyngeal carcinoma.
- Induces IFN-γ secreting cells at a frequency of 80.6 SFC/5x10⁴ CD8+ T cells (at 20 μg/mL for 24 h).
- Significantly increases the proportion of CD8+IFN-γ+ cells after two weeks of stimulation (at 20 μg/mL).
- Specific CTLs effectively kill peptide-pulsed T2 cells and 293T-LMP2A cells (at 20 μg/mL for 4 h).
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 10 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound used as an indicator of perfluorinated compound pollution in ecosystems. It has shown certain toxicity in mice and can impact planktonic microbial communities. This product is for research use only.
- Serves as an indicator of perfluorinated compound pollution
- Exhibits toxicity to mice
- Affects planktonic microbial communities
- Available with downloadable data sheet, COA, and SDS
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 25 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound that serves as an important indicator of perfluorinated compound pollution in ecosystems. It has been observed to affect planktonic microbial communities and show certain toxicity in mice studies.
- Indicator of perfluorinated compound pollution
- Impacts planktonic microbial communities
- Can threaten water quality via microbial metabolism
- In vivo studies suggest potential for liver damage and skin inflammation
Medchemexpress LLC GluN1(356-385) | 99.95% | 3415.90 | 5 MG
GluN1 (356-385) is an antigenic peptide used against N-methyl-D-aspartate receptor (NMDAR) encephalitis. It effectively reduces the density of surface NMDAR clusters in hippocampal neurons. This peptide can be utilized to investigate the pathogenesis of anti-NMDAR encephalitis.
- Antigenic peptide against N-methyl-D-aspartate receptor (NMDAR) encephalitis.
- Reduces the density of surface NMDAR clusters in hippocampal neurons.
- Useful for studying the pathogenesis of anti-NMDAR encephalitis.
- Purity of 99.95%.
Medchemexpress LLC Perfluoropentanoic acid | 2706-90-3 | 98.0% | 264.05 | 1 G
Perfluoropentanoic acid (PFPeA) is a short-chain perfluorinated compound used as an important indicator of perfluorinated compound pollution in ecosystems. It exhibits certain toxicity to mice and is intended for research use only.
- Short-chain perfluorinated compound.
- Indicator of perfluorinated compound pollution.
- Exhibits toxicity to mice, affecting liver, skin, and immune cells.
- Can impact planktonic microbial communities and water quality.
- Increases serum and urine concentrations after topical application.
- Alters gene expression related to lipid metabolism and inflammation.
Cayman Chemical HeptafluorobutyrIc AcId 100g
A perfluoroalkyl substance; chronic topical administration on the EAr increases liver and kidney weight in mice at 25 µl of a 3.75-15% v/v on the EAr; induces multifocal hepatocyte necrosis and centrilobular hepatocyte hypertrophy at 7.5% v/v; increases serum cholesterol and ALP levels at 15% v/v; decreases serum urea nitrogen levels; has been found in marine life and as a contaminant in surface water
Medchemexpress LLC GluN1(356-385) | 99.95% | 3415.90 | 1 MG
GluN1 (356-385) is an antigenic peptide developed for the study of N-methyl-D-aspartate receptor (NMDAR) encephalitis. It functions by reducing the density of surface NMDAR clusters in hippocampal neurons, offering a tool to understand the pathogenesis of anti-NMDAR encephalitis.
- Antigenic peptide against NMDAR encephalitis
- Reduces density of surface NMDAR clusters in hippocampal neurons
- Useful for studying anti-NMDAR encephalitis pathogenesis
Cambridge Isotope Laboratories 2H 2H 3H 3H-Perfluorohexanoic acid (3 3 FTCA) (unlabeled) 100 ug/mL in methanol 1 2 mL
2H 2H 3H 3H-Perfluorohexanoic acid (3 3 FTCA) (unlabeled) 100 ug/mL in methanol 1 2 mL
Cayman Chemical 2H 2H 3H 3H-Perfluorodecanoic
A polyfluoroalkyl substance; has been found as a contaminant in freshwater reserves and marine seafood
Matrix Scientific PENTAFLUOROPROPIONIC ACID MF C3HF5O2 MW 164.03 CAS 422-64-0 MDL MFCD00004170 QTY 25 UOM G
PENTAFLUOROPROPIONIC ACID MF C3HF5O2 MW 164.03 CAS 422-64-0 MDL MFCD00004170 QTY 25 UOM G
Medchemexpress LLC X-376 | 1365267-27-1 | 98.1% | 547.41 g·mol⁻¹ | C25H25Cl2FN6O3 | 10 MG
X-376 is a small-molecule tyrosine kinase inhibitor that potently targets anaplastic lymphoma kinase (ALK) and shows inhibitory activity against MET. It is supplied as a powder for preclinical research use and is suitable for cellular and in vivo studies of ALK-driven tumors.
- Potent ALK inhibition (IC50 0.61 nM).
- MET inhibitory activity (IC50 0.69 nM).
- Suitable for preclinical cellular and in vivo research.
- Supplied as a powder with recommended cold storage for stability.
- Molecular weight 547.41 g·mol⁻¹; formula C25H25Cl2FN6O3.