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Halomethanes

Organic compounds in which one or more of the hydrogens in methane is replaced with a halogen atom; halogen atoms include bromine, chlorine, fluorine, iodine.

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Medchemexpress LLC (7S)-BAY-593 | 2413068-25-2 | 99.61% | 476.53 | 10 MM * 1 ML
SDP

(7S)-BAY-593 is the S-enantiomer of BAY-593, an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity.

  • Inhibits YAP1/TAZ signaling
  • Exhibits antitumor activity
  • Orally active GGTase-I inhibitor

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2

Medchemexpress LLC 2-cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- | 220757-88-0 | 99.1% | 364.60 | C24H44O2 | 10 MG
SDP

tCFA15 is a trimethyl cyclohexenonic long-chain fatty alcohol (C24H44O2, MW 364.60) that promotes neuronal differentiation and modulates Notch1 signaling. It is supplied as a high-purity research standard intended for in vitro studies of neural stem cell differentiation and neuronal signaling pathways.

  • Promotes differentiation of neural stem cell-derived neurospheres toward neurons.
  • Modulates Notch1 expression and signaling.
  • High purity suitable for in vitro research applications.
  • Soluble in DMSO for solution-based assays.
  • Shown to stimulate arginine vasopressin secretion in neurohypophysis preparations.

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3

Medchemexpress LLC N-[5-({2-[(cyclopropylcarbonyl)amino]-imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-... | 1005780-62-0 | MFCD23160045 | 99.7% | 445.47 g·mol⁻1 | C23H23N7O3 | 10 MG
SDP

TAK-593 is a small-molecule tyrosine kinase inhibitor originally developed by Takeda Pharmaceutical Company. It potently inhibits vascular endothelial growth factor receptors and platelet-derived growth factor receptors and has demonstrated anti-angiogenic and antitumor activity in preclinical studies. Reported biochemical IC50 values include 3.2 nM (VEGFR1), 0.95 nM (VEGFR2), 1.1 nM (VEGFR3), 4.3 nM (PDGFRα), and 13 nM (PDGFRβ).

  • Potent VEGFR and PDGFR inhibition (VEGFR2 IC50 ≈ 0.95 nM).
  • High biochemical selectivity toward receptor tyrosine kinases.
  • Reported molecular formula C23H23N7O3 and molecular weight ≈ 445.47 g·mol⁻1.
  • High purity, typically reported as 99.66% by supplier.
  • Provided with analytical documentation such as LC-MS.
  • Suitable for preclinical studies of angiogenesis and tumor biology.

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