Anthracenes
![Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)carbonyl]-, 2-methoxyethyl ester, magnesium salt (2:1) | 1224964-36-6 | 98.25% | 548.92 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000402905-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1-Piperazinecarboxylic acid, 4-[[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl]-3-[(hydroxyamino)carbonyl]-, 2-methoxyethyl ester, magnesium salt (2:1) | 1224964-36-6 | 98.25% | 548.92 | 25 MG
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor. It exhibits IC50s of approximately 1900, 0.81, 120, 10.8, 18, and 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It is a highly potent, low-molecular-weight inhibitor of MMPs with very limited aqueous solubility. It potently inhibits MMP-2, MMP-13, and ADAM10 [TNF-α-converting enzyme (TACE)] activity in vitro, with IC50 values in the range of 1-2 nM. It also inhibits MMP-9 (IC50 ~20 nM) and ADAM17 (IC50 ~70 nM) activity. However, it shows low potency for inhibiting MMP-1 (IC50 ~2,000 nM).
- Selective matrix metalloproteinases (MMP) inhibitor.
- Potently inhibits MMP-2, MMP-13, ADAM10, MMP-9, and ADAM17 activities.
- Used for research purposes only.
- Available in solid and solution forms.
Accela Chembio Inc MF: C15H12O | MW: 208.26 | ?98% | Flash Point: 196.3?.
MF: C15H12O | MW: 208.26 | ?98% | Flash Point: 196.3?.
eMolecules Ethyl 10-bromoanthracene-9-carboxylate | 1089318-91-1 | MFCD22571679 | 1g
Ambeed | Ethyl 10-bromoanthracene-9-carboxylate | 1g | 600831862 | A164059 | | 1089318-91-1 | MFCD22571679 | 329.193 | C17H13BrO2
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Sigma Aldrich Fine Chemicals Biosciences Triptycene 98% | 477-75-8 | MFCD00003813 | 1G
Triptycene 98% | Purity: 98% | Mol Wt: 254.33 | 477-75-8 | MFCD00003813 | 1G
![Sigma Aldrich Fine Chemicals Biosciences Dibenz[a,j]anthracene BCR(R), certified reference material | 224-41-9 | MFCD00215859 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501762352.PNG-250.jpg)
Sigma Aldrich Fine Chemicals Biosciences Dibenz[a,j]anthracene BCR(R), certified reference material | 224-41-9 | MFCD00215859 | 100MG
Dibenz[a,j]anthracene BCR(R), certified reference material | Mol Wt: 278.35 | 224-41-9 | MFCD00215859 | 100MG
Sigma Aldrich Fine Chemicals Biosciences 9-Bromoanthracene 94% | Purity: 94% | Mol Wt: 257.13 | 1564-64-3 | MFCD00001243 | 25G
9-Bromoanthracene 94% | Purity: 94% | Mol Wt: 257.13 | 1564-64-3 | MFCD00001243 | 25G
Medchemexpress LLC 9-Bromoanthracene-d9 | 183486-02-4 | 266.18 | 5 G
9-Bromoanthracene-d9 is a deuterium-labeled version of 9-Bromoanthracene. It is intended for research use only and is not sold to patients. This compound can be utilized as a tracer and an internal standard for quantitative analysis. Its appearance is a solid, light yellow to yellow in color.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
eMolecules Anthracene-9-thiocarboxamide | 1347815-19-3 | MFCD20265376 | 1g
Oakwood Chemicals | Anthracene-9-thiocarboxamide | 1g | 480147474 | 097934 | | 1347815-19-3 | MFCD20265376 | 237.320 | C15H11NS
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eMolecules 9,10-Dimethylanthracene | 781-43-1 | MFCD00001262 | 10g
Combi-Blocks | 9,10-Dimethylanthracene | 10g | 482934476 | QF-5809 | 95.000 | 781-43-1 | MFCD00001262 | 206.288 | C16H14
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eMolecules Target Molecule TAK-779 50mg 517682758 T7499 0 000 229005-80-5 MFCD05662319 531 140 C33H39ClN2O2
Target Molecule TAK-779 50mg 517682758 T7499 0 000 229005-80-5 MFCD05662319 531 140 C33H39ClN2O2
Medchemexpress LLC A 779 | 159432-28-7 | 99.3% | 872.97 | 100 MG
A 779 is a specific antagonist of the G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII. It is for research use only.
- Inhibits the effect of Ang-(1-7)
- Suppresses PCNA protein expression up-regulated by Ang II
- Blocks Ang II-induced inflammatory responses of VSMCs
- Blocks Ang II-induced Akt and ERK1/2 phosphorylation
- Elevates serum BALP, CTX, TRAcP 5b, OC, and urinary DPD
- Abolishes Ang-(1-7)'s favorable effects on bone health by blocking the Mas receptor
- Erradicates captopril protective effects on bone metabolism, mineralization, and micro-structure
- Restores OVX effects on RANKL expression and ACE-1/AngII/AT1R cascade
- Down-regulates OPG expression and ACE-2/Ang1-7/Mas pathway