Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

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2,956 – 2,970 of 5,849 results

2,956

Medchemexpress LLC C12-iE-DAP hydrochloride | 538.07 | 1 MG

C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP, a biologically active peptide with agonistic effects on NOD1. It targets the NOD-like Receptor (NLR) and plays a role in immunology and inflammation pathways.

Hydrochloride salt form
Biologically active peptide
Agonistic effects on NOD1
Molecular formula: C24H44ClN3O8
Sequence: Lauroyl-γ-d-Glu-meso-diaminopimelic acid
Targets NOD-like Receptor (NLR)
Involved in immunology/inflammation pathways

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2,957

Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 500 MG

Loperamide hydrochloride is an opioid receptor agonist and a selective human intestinal carboxylesterases (hiCE) inhibitor, known for its anti-diarrheal effect. This compound has a molecular formula of C29H34Cl2N2O2 and a molecular weight of 513.50. It is intended for research use only and has not been fully validated for medical applications.

Opioid receptor agonist
Selective and competitive human intestinal carboxylesterases inhibitor
Demonstrates anti-diarrheal properties
Induces ER stress and autophagy in certain cell lines (in vitro)
Decreases specific protein lipidation levels in ATF4 KO cells (in vitro)
Suitable for laboratory research purposes

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2,958

Medchemexpress LLC Cephalexin hydrochloride | 59695-59-9 | 99.8% | 100 MG

Cephalexin hydrochloride is a potent, orally active, semisynthetic cephalosporin antibiotic. It demonstrates a broad antibacterial spectrum against various gram-positive and gram-negative bacteria by targeting penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. It is utilized in research for conditions such as pneumonia, strep throat, and bacterial endocarditis.

Potent, orally active, semisynthetic cephalosporin antibiotic
Broad antibacterial spectrum against gram-positive and gram-negative bacteria
Inhibits bacterial cell wall assembly by targeting penicillin-binding proteins
Disrupts polymer peptidoglycan biogenesis at 10 μg/mL
Exhibits antibacterial activity in animal models
Used in research for pneumonia, strep throat, and bacterial endocarditis

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2,959

Medchemexpress LLC Quinpirole (hydrochloride) | 85798-08-9 | 25 MG

Quinpirole hydrochloride is a high-affinity agonist of the dopamine D2/D3 receptor. It is also known as LY 171555 hydrochloride or (-)-LY 141865 hydrochloride. Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist that can reduce hypothalamic norepinephrine concentrations. Its effects, which include a decrease in dopamine metabolites and a possible increase in MHPG sulfate by enhancing norepinephrine release, are not replicated by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity.

High-affinity agonist of dopamine D2/D3 receptor.
Reduces hypothalamic norepinephrine concentrations.
Leads to a decrease in dopamine metabolites.
May increase MHPG sulfate by enhancing norepinephrine release.

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2,960

Ambeed AMBEED

5000869116 2-METHYL-1-NAPHTHOL 1GR

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2,961

Medchemexpress LLC MK-571 (sodium) | 115103-85-0 | L-660711 (sodium) | 99.75% | 537.07 | 50 MG

MK-571 (L-660711) sodium is an orally active, potent, and selective competitive leukotriene D4 (LTD4) receptor antagonist, with Ki values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. It is also an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release.

Orally active.
Potent and selective competitive leukotriene D4 (LTD4) receptor antagonist.
Inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1).
Inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release.
Appearance: solid, light yellow to yellow.

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2,962

Ambeed AMBEED

5000871198 NAPHTHOLBENZEIN 5GR

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2,963

Sigma Aldrich Fine Chemicals Biosciences Adapalene >=98% (HPLC) | 106685-40-9 | MFCD03106112 | 50MG

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2,964

Sigma Aldrich Fine Chemicals Biosciences 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate|18108-68-4|MFCD16661224|25g

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate | Purity: 95% | MW: 310.49 | 18108-68-4 | MFCD16661224 | 25g

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2,965

Medchemexpress LLC BI 2536 | 755038-02-9 | 99.9% | 50 MG

BI 2536 is a dual inhibitor targeting both PLK1 (Polo-like Kinase 1) and BRD4 (Bromodomain-containing protein 4), with IC50 values of 0.83 nM and 25 nM, respectively. It suppresses IFNB (Interferon-beta) gene transcription and exhibits antiproliferative activity against various human cancer cell lines. This product is intended for research use only.

Targets PLK1 and BRD4
High potency (IC50 of 0.83 nM for PLK1 and 25 nM for BRD4)
Suppresses IFNB gene transcription
Demonstrated antiproliferative activity against a wide range of human cancer cell lines
Available in solid form and as a 10 mM solution in DMSO
Purity of 99.9%

Pricing & Availability

2,966

Medchemexpress LLC Cysteamine (hydrochloride) | 156-57-0 | 99.3% | C2H8ClNS | 25 G

Cysteamine hydrochloride is an orally active agent for treating nephropathic cystinosis and functions as an antioxidant. It elevates intracellular glutathione in cystinotic cells, restoring redox balance and mitigating apoptosis. The compound also exhibits antioxidant properties by scavenging reactive oxygen species and boosting glutathione production, and it enhances the production of heat shock proteins.

Treats nephropathic cystinosis and acts as an antioxidant.
Increases intracellular glutathione levels in cystinotic cells.
Counteracts increased apoptosis in cystinotic cells.
Scavenges OH, HOCl, and reacts with H2O2.
Enhances production of heat shock proteins (HSP).
Exerts dose-dependent effect on doxorubicin-induced cancer cell death.

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2,967

Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 MG

BI-2865 is a non-covalent pan-KRAS inhibitor. It binds to wild-type (WT) and several mutant KRAS forms, including G12C, G12D, G12V, and G13D, with KDs ranging from 4.3 to 32 nM. This compound effectively inhibits the proliferation of G12C, G12D, or G12V mutant KRAS expressing BaF3 cells, showing a mean IC50 of approximately 140 nM.

Binds to multiple KRAS mutants (WT, G12C, G12D, G12V, G13D)
Inhibits proliferation of KRAS mutant expressing BaF3 cells
Derivative with a prolinol substituent and a pyrimidine linker
Exhibits direct ionic interaction with E62 and a water-mediated hydrogen bond network

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2,968

Medchemexpress LLC Atrasentan hydrochloride | 195733-43-8 | C29H39ClN2O6 | 100 MG

Atrasentan hydrochloride is a selective endothelin A receptor antagonist, exhibiting an IC50 of 0.0551 nM for ETA. It is designated for research purposes only and is not intended for patient use. This compound presents as an off-white to gray solid with a molecular weight of 547.08.

Effectively inhibits the growth of LNCaP and C4-2b prostate cancer cells.
Significantly induces several CYPs and drug transporters.
Acts as a moderate P-gp inhibitor and a weak BCRP inhibitor.
Suppresses pressor response initiated by big endothelin-1 in pithed rats.
Partially inhibits C4-2b tumor progression within the bone environment in the SCID-hu model.
Soluble in DMSO and water with specific preparation requirements.
Recommended storage at 4°C in sealed conditions, away from moisture.

Pricing & Availability

2,969

Sigma Aldrich Fine Chemicals Biosciences 8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate for fluorescence, >=95% (perchloric acid titration) | 18108-68-4 | MFCD16661224 | 5G

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate for fluorescence, >=95% (perchloric acid titration) | Purity: >=95% (perchloric acid titration) | 18108-68-4 | MFCD16661224 | 5G

Pricing & Availability

2,970

Cayman Chemical Lovastatin Hydroxy Acid sodi

A potent and competitive HMG-CoA reductase inhibitor (Ki = 0.6 nM); is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin

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Naphthalenes

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Medchemexpress LLC C12-iE-DAP hydrochloride | 538.07 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cephalexin hydrochloride | 59695-59-9 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quinpirole (hydrochloride) | 85798-08-9 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MK-571 (sodium) | 115103-85-0 | L-660711 (sodium) | 99.75% | 537.07 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI 2536 | 755038-02-9 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cysteamine (hydrochloride) | 156-57-0 | 99.3% | C2H8ClNS | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-2865 | 2937327-93-8 | C23H27N7O2S | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Atrasentan hydrochloride | 195733-43-8 | C29H39ClN2O6 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More