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Filtered Search Results
eMolecules Synthonix 5-Cyanovalerylzinc bromide 0.50 M in THF 25ml 703157758 C73678 1443250-11-0 MFCD08741503 241.440 C6H10BrNZn
Synthonix 5-Cyanovalerylzinc bromide 0.50 M in THF 25ml 703157758 C73678 1443250-11-0 MFCD08741503 241.440 C6H10BrNZn
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eMolecules 210407-20-8 | (4-Bromophenyl)zinc bromide, 0.5 M in THF | Synthonix301.290 | C6H4Br2Zn | 0.000 | [Br-].[Zn+]c1ccc(Br)cc1 | 100ml | 818572010
(4-Bromophenyl)zinc bromide, 0.5 M in THF | Synthonix | 210407-20-8301.290 | C6H4Br2Zn | 0.000 | [Br-].[Zn+]c1ccc(Br)cc1 | 100ml | 818572010
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eMolecules 328000-17-5 | 4-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1ccc(cc1)C1OCCO1 | 50ml | 779536146
4-(1,3-Dioxolan-2-yl)phenylmagnesium bromide, 0.5 M in THF | Synthonix | 328000-17-5253.378 | C9H9BrMgO2 | 97.000 | [Br-].[Mg+]c1ccc(cc1)C1OCCO1 | 50ml | 779536146
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Medchemexpress LLC BI-4020 | 2664214-60-0 | 99.3% | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M, and primary mutant EGFR del19 (IC50=1 nM). It also shows activity against EGFR wt (IC50=190 nM). This product demonstrates high kinome selectivity and good DMPK properties and is for research use only.
- Fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor
- Inhibits triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM)
- Inhibits double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM)
- Shows activity against EGFR wt (IC50=190 nM)
- Demonstrates high kinome selectivity and good DMPK properties
- Leads to tumor regressions in human PC-9 triple mutant NSCLC xenograft model in mice
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eMolecules 312693-11-1 | 1-Ethylpentylzinc bromide, 0.50 M in THF | Synthonix244.480 | C7H15BrZn | 0.000 | [Br-].CCCCC([Zn+])CC | 100ml | 532652800
1-Ethylpentylzinc bromide, 0.50 M in THF | Synthonix | 312693-11-1244.480 | C7H15BrZn | 0.000 | [Br-].CCCCC([Zn+])CC | 100ml | 532652800
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eMolecules 17217-57-1 | MeO-bpy | ChemScene | MFCD00233880 | 216.240 | C12H12N2O2 | 98.000 | COc1ccnc(c1)-c1cc(OC)ccn1 | 5g | 572231378
MeO-bpy | ChemScene | 17217-57-1 | MFCD00233880 | 216.240 | C12H12N2O2 | 98.000 | COc1ccnc(c1)-c1cc(OC)ccn1 | 5g | 572231378
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eMolecules 62890-98-6 | 2,5-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | MFCD01311475 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc(OC)c([Mg+])c1 | 50ml | 437237129
2,5-Dimethoxyphenylmagnesium bromide, 0.5 M in THF | Synthonix - Stock | 62890-98-6 | MFCD01311475 | 241.367 | C8H9BrMgO2 | 0.000 | [Br-].COc1ccc(OC)c([Mg+])c1 | 50ml | 437237129
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eMolecules (2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
(2-Phenanthryl)zinc bromide, 0.25 M in THF | Synthonix |322.510 | C14H9BrZn | 0.000 | [Br-].[Zn+]c1ccc2c(ccc3ccccc23)c1 | 50ml | 818572034
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eMolecules Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
Synthonix 5-Bromo-2-thienylzinc bromide 0.50 M in THF 50ml 532652648 B73258 151073-94-8 MFCD00671986 307.310 C4H2Br2SZn
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eMolecules 204324-71-0 | (3,5-Ditert-butylphenyl)magnesium bromide, 0.5 M in THF | Synthonix293.531 | C14H21BrMg | 0.000 | [Br-].CC(C)(C)c1cc([Mg+])cc(c1)C(C)(C)C | 50ml | 812584972
(3,5-Ditert-butylphenyl)magnesium bromide, 0.5 M in THF | Synthonix | 204324-71-0293.531 | C14H21BrMg | 0.000 | [Br-].CC(C)(C)c1cc([Mg+])cc(c1)C(C)(C)C | 50ml | 812584972
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eMolecules [3-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)propyl]zinc bromide, 0.50 M in THF | Synthonix |345.740 | C9H22BrNSi2Zn | 0.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Zn+] | 100ml | 794559329
[3-(2,2,5,5-tetramethyl-1,2,5-azadisilolidin-1-yl)propyl]zinc bromide, 0.50 M in THF | Synthonix |345.740 | C9H22BrNSi2Zn | 0.000 | [Br-].C[Si]1(C)CC[Si](C)(C)N1CCC[Zn+] | 100ml | 794559329
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eMolecules 123061-49-4 | 2-(Methylthio)-4-(tributylstannyl)pyrimidine | Synthonix - Stock | MFCD01319026 | 415.230 | C17H32N2SSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(SC)n1 | 1g | 525920339
2-(Methylthio)-4-(tributylstannyl)pyrimidine | Synthonix - Stock | 123061-49-4 | MFCD01319026 | 415.230 | C17H32N2SSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(SC)n1 | 1g | 525920339
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Medchemexpress LLC Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
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Butenafine Hydrochloride | 101827-46-7 | 99.9% | 353.93 | 5 G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 1037176-29-6 | 5-Fluoropentylzinc bromide, 0.50 M in THF | Synthonix234.420 | C5H10BrFZn | 98.000 | [Br-].FCCCCC[Zn+] | 50ml | 702445914
5-Fluoropentylzinc bromide, 0.50 M in THF | Synthonix | 1037176-29-6234.420 | C5H10BrFZn | 98.000 | [Br-].FCCCCC[Zn+] | 50ml | 702445914
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eMolecules (3-Chloro-5-cyanophenyl)zinc bromide, 0.5 M in THF | Synthonix |281.840 | C7H3BrClNZn | 0.000 | [Br-].Clc1cc([Zn+])cc(c1)C#N | 100ml | 812584955
(3-Chloro-5-cyanophenyl)zinc bromide, 0.5 M in THF | Synthonix |281.840 | C7H3BrClNZn | 0.000 | [Br-].Clc1cc([Zn+])cc(c1)C#N | 100ml | 812584955
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