Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

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4,291 – 4,305 of 5,856 results

4,291

eMolecules 131865-59-3 | N-Succinimidyl-5-(tri-butylstannyl)-3-pyridinecarboxylate | Synthonix - Stock | MFCD30724039 | 509.234 | C22H34N2O4Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1cncc(c1)C(=O)ON1C(=O)CCC1=O | 1g | 525923257

N-Succinimidyl-5-(tri-butylstannyl)-3-pyridinecarboxylate | Synthonix - Stock | 131865-59-3 | MFCD30724039 | 509.234 | C22H34N2O4Sn | 95.000 | CCCC[Sn](CCCC)(CCCC)c1cncc(c1)C(=O)ON1C(=O)CCC1=O | 1g | 525923257

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4,292

eMolecules 1155294-76-0 | (9,9-Dimethylfluoren-2-yl)magnesium bromide, 0.5 M in THF | Synthonix297.478 | C15H13BrMg | 0.000 | [Br-].CC1(C)c2ccccc2-c2ccc([Mg+])cc12 | 100ml | 812584970

(9,9-Dimethylfluoren-2-yl)magnesium bromide, 0.5 M in THF | Synthonix | 1155294-76-0297.478 | C15H13BrMg | 0.000 | [Br-].CC1(C)c2ccccc2-c2ccc([Mg+])cc12 | 100ml | 812584970

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4,293

TARGETMOL CHEMICALS INC BI-2865 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. BI-2865 is a non-covalent pan-KRAS inhibitor.BI-2865 binds to KRAS WT G12C G12D G12V and G13D mutants with KD values of 6.9 4.5 32 26 and 4.3 nM respectively.BI-2865 showed antiproliferative activity in BaF3 cells expressing KRAS G12C G12D or G12V mutants. BI-2865 showed antiproliferative activity on BaF3 cells expressing KRAS G12C G12D or G12V mutants with an average IC50 value of approximately 140 nM. purity: 99%

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4,294

Medchemexpress LLC BI-749327 | 2361241-23-6 | 99.9% | 442.43 | 1 MG

BI-749327 is a potent, highly selective, and orally bioavailable TRPC6 antagonist. It demonstrates significant selectivity, being 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7. In vitro, it suppresses NFAT activation and blocks signaling of prohypertrophic genes in isolated myocytes.

Potent and selective TRPC6 antagonist
Orally bioavailable
Suppresses NFAT activation in HEK293T cells
Blocks prohypertrophic gene expression in isolated myocytes
Improves left heart function and reduces volume/mass ratio in vivo
Reduces renal fibrosis in vivo
Long terminal half-life in mice

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4,295

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 25 MG

Stimulates alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells
Increases glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure
Serves as an analytical standard
Suitable for research and analytical applications

Pricing & Availability

4,296

Medchemexpress LLC BI-4020 | 2664214-60-0 | 98.82% | 50 MG

BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. It exhibits high kinome selectivity and favorable DMPK properties. This compound is stable under recommended storage conditions.

Inhibits the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines).
Inhibits the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM).
Shows activity against EGFR wt (IC50=190 nM).
For research use only by suitably qualified experienced scientists.

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4,297

Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 1 ML

Loperamide hydrochloride (R-18553 hydrochloride) is an opioid receptor agonist and a selective, competitive human intestinal carboxylesterases (hiCE) inhibitor. It is primarily recognized for its anti-diarrheal effects and is extensively used in research settings to study its impact on various biological pathways.

Induces hallmarks of ER stress and autophagy in GBM cells and MEFs.
Decreases LC3B and GABARAP lipidation levels in ATF4 KO cells compared to WT cells.
Used in cell autophagy assays.
Store at 4°C, sealed and away from moisture.
For solutions, store at -80°C for up to 6 months or -20°C for 1 month, sealed and away from moisture.
Shipped at room temperature for durations less than 2 weeks.

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4,298

Medchemexpress LLC Ivabradine (hydrochloride) | 148849-67-6 | 99.7% | 100 MG

Ivabradine (hydrochloride) is a potent and orally active blocker of HCN (hyperpolarization-activated cyclic nucleotide-gated) channels. It inhibits the cardiac pacemaker current (If) and is known to reduce heart rate in a dose-dependent manner without affecting blood pressure. This compound exhibits anticonvulsant, anti-ischaemic, and anti-anginal activities, making it suitable for various research applications.

Potent and orally active HCN channel blocker
Inhibits cardiac pacemaker current (If)
Reduces heart rate dose-dependently without affecting blood pressure
Exhibits anticonvulsant activity
Exhibits anti-ischaemic activity
Exhibits anti-anginal activity
Intended for research and analytical applications
Purity of 99.7%

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4,299

Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 98.4% | 302.71 | 25 MG

Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. It is a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels.

Potent and orally active purine nucleoside phosphorylase (PNP) inhibitor.
Inhibits human lymphocyte proliferation.
Induces apoptosis in leukemic cells.
Excellent oral bioavailability in mice.
Effective in prolonging life span in mouse models.

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4,300

Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 99.9% | 302.71 | 1 ML

Forodesine hydrochloride is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor. It acts as a potent human lymphocyte proliferation inhibitor and can induce apoptosis in leukemic cells by increasing dGTP levels. It has excellent oral bioavailability in mice.

Highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor
Potent human lymphocyte proliferation inhibitor
Induces apoptosis in leukemic cells
Excellent oral bioavailability in mice

Pricing & Availability

4,301

Medchemexpress LLC L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1) | 1421-65-4 | 99.8% | 247.68 | 1 G

Melevodopa hydrochloride is an effervescent Levodopa prodrug. Levodopa is an orally active metabolic precursor of neurotransmitters dopamine and has anti-allodynic effects and the potential for Parkinson's disease.

Solid appearance
White to off-white color
Soluble in DMSO
Store at 4°C under nitrogen
Store in solvent at -80°C for 6 months, or -20°C for 1 month under nitrogen

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4,302

Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | 99.15% | 262.73 | 100 MG

Neocuproine hydrochloride monohydrate can be used to prepare complex solutions for studying antioxidant capacity determination in biological samples based on copper reduction complexes.

Used for research purposes only
High purity: 99.15%
Available in solid appearance
Color: Off-white to light yellow
Soluble in DMSO
Store at room temperature, keep dry and cool

Pricing & Availability

4,303

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 1 ML

Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. It can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Research indicates Octopamine hydrochloride increases glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure.

Acts as a neurohormone, neuromodulator, and neurotransmitter in invertebrates.
Stimulates alpha2-adrenoceptors (ARs).
Increases glycogenolysis and glycolysis.
Enhances oxygen uptake.
Boosts gluconeogenesis.
Elevates portal perfusion pressure.

Pricing & Availability

4,304

Medchemexpress LLC Loperamide hydrochloride (Standard) | 34552-83-5 | 99.9% | 100 MG

Loperamide hydrochloride (Standard) is the analytical standard of Loperamide (hydrochloride). It acts as an opioid receptor agonist and is recognized as a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor, exhibiting an anti-diarrheal effect. This product is intended for research and analytical applications.

Used as a reference standard for assay purposes.
Commonly utilized in qualitative, quantitative, and methodological research experiments.
Suitable for techniques such as HPLC, GC, and MS.

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4,305

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | MFCD00012881 | 99.90% | 5 G

Octopamine hydrochloride is a biogenic monoamine structurally related to noradrenaline. It functions as a neurohormone, neuromodulator, and neurotransmitter in invertebrates, stimulating alpha2-adrenoceptors. This compound is known to affect various physiological processes, including metabolism and neuroregulation. It achieves its effects by binding to specific G protein-coupled receptors.

Regulates sensory input desensitization, arousal, and complex behaviors like learning and memory.
Modulates endocrine gland activity.
Mobilizes lipids and carbohydrates as a neurohormone.
Stimulates alpha2-adrenoceptors.
Increases glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis, and portal perfusion pressure.

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Naphthalenes

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TARGETMOL CHEMICALS INC BI-2865 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-749327 | 2361241-23-6 | 99.9% | 442.43 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-4020 | 2664214-60-0 | 98.82% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Loperamide hydrochloride | 34552-83-5 | 99.8% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ivabradine (hydrochloride) | 148849-67-6 | 99.7% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 98.4% | 302.71 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Forodesine hydrochloride | 284490-13-7 | 99.9% | 302.71 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1) | 1421-65-4 | 99.8% | 247.68 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | 99.15% | 262.73 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Loperamide hydrochloride (Standard) | 34552-83-5 | 99.9% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Octopamine hydrochloride | 770-05-8 | MFCD00012881 | 99.90% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More