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Filtered Search Results
eMolecules 500789-41-3 | 4-tert-Butyl 2-methyl morpholine-2,4-dicarboxylate | Combi-Blocks | MFCD16877230 | 245.275 | C11H19NO5 | 97.000 | COC(=O)C1CN(CCO1)C(=O)OC(C)(C)C | 5g | 485192374
4-tert-Butyl 2-methyl morpholine-2,4-dicarboxylate | Combi-Blocks | 500789-41-3 | MFCD16877230 | 245.275 | C11H19NO5 | 97.000 | COC(=O)C1CN(CCO1)C(=O)OC(C)(C)C | 5g | 485192374
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Medchemexpress LLC Ombrabulin hydrochloride | 253426-24-3 | 99.4% | 438.90 | 25 MG
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Ombrabulin hydrochloride | 253426-24-3 | 99.4% | 438.90 | 25 MG
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eMolecules 6052-73-9 | 5,6-Dihydropyridin-2(1H)-one | Combi-Blocks | MFCD19216835 | 97.117 | C5H7NO | 97.000 | O=C1NCCC=C1 | 5g | 401043033
5,6-Dihydropyridin-2(1H)-one | Combi-Blocks | 6052-73-9 | MFCD19216835 | 97.117 | C5H7NO | 97.000 | O=C1NCCC=C1 | 5g | 401043033
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![eMolecules 402-26-6 | (3-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1cccc([Mg+])c1 | 100ml | 702445992](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694914.jpg-250.jpg)
eMolecules 402-26-6 | (3-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1cccc([Mg+])c1 | 100ml | 702445992
(3-(trifluoromethyl)phenyl)magnesium bromide, 0.50 M in THF | Synthonix | 402-26-6249.313 | C7H4BrF3Mg | 0.000 | [Br-].FC(F)(F)c1cccc([Mg+])c1 | 100ml | 702445992
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eMolecules 2386-58-5 | Ethenesulfonamide | ChemScene | MFCD00051751 | 107.130 | C2H5NO2S | 97.000 | NS(=O)(=O)C=C | 1g | 572289931
Ethenesulfonamide | ChemScene | 2386-58-5 | MFCD00051751 | 107.130 | C2H5NO2S | 97.000 | NS(=O)(=O)C=C | 1g | 572289931
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![eMolecules 352530-42-8 | 2,4-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260174 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1ccc([Zn+])c(Cl)c1 | 50ml | 532652746](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696242.jpg-250.jpg)
eMolecules 352530-42-8 | 2,4-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260174 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1ccc([Zn+])c(Cl)c1 | 50ml | 532652746
2,4-Dichlorophenylzinc iodide, 0.50 M in THF | Synthonix | 352530-42-8 | MFCD02260174 | 338.270 | C6H3Cl2IZn | 0.000 | [I-].Clc1ccc([Zn+])c(Cl)c1 | 50ml | 532652746
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Medchemexpress LLC BI-0474 | 2750570-55-7 | 99.8% | 587.74 | 50 MG
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BI-0474 is a potent KRASG12C inhibitor that demonstrates an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. It exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation and shows good anti-tumour activity in non-small cell lung cancer xenograft models. Designed by Boehringer Ingelheim, this compound is available for research use only.
- Potent KRASG12C inhibitor
- IC50 value of 7.0 nM for GDP-KRAS::SOS1 protein-protein interaction
- Demonstrates anti-proliferative activity against NCI-H358 cells with G12C mutation
- Shows anti-tumour activity in non-small cell lung cancer xenograft models
- For research use only
- Purity of 99.83%
- Molecular weight of 587.74
- Chemical formula is C30H37N9O2S
- Appears as a white to off-white solid
- Target: KRAS-SOS1
- EC50 = 26 nM on NCI-H358 cells (G12C mutant)
- Soluble in DMSO at 100 mg/mL
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(CCCC)c1ccnc(C)c1 | 5g | 525921461](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696658.jpg-250.jpg)
eMolecules 134914-97-9 | 2-Methyl-4-(tributylstannyl)pyridine | Synthonix - Stock | MFCD16039584 | 382.179 | C18H33NSn | 98.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(C)c1 | 5g | 525921461
2-Methyl-4-(tributylstannyl)pyridine | Synthonix - Stock | 134914-97-9 | MFCD16039584 | 382.179 | C18H33NSn | 98.000 | CCCC[Sn](CCCC)(CCCC)c1ccnc(C)c1 | 5g | 525921461
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![eMolecules 307496-33-9 | 2,6-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(F)c1C[Zn+] | 50ml | 532652762](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696226.jpg-250.jpg)
eMolecules 307496-33-9 | 2,6-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(F)c1C[Zn+] | 50ml | 532652762
2,6-Difluorobenzylzinc bromide, 0.50 M in THF | Synthonix | 307496-33-9272.400 | C7H5BrF2Zn | 0.000 | [Br-].Fc1cccc(F)c1C[Zn+] | 50ml | 532652762
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![eMolecules 497923-83-8 | 2-Chloro-4-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260160 | 321.820 | C6H3ClFIZn | 0.000 | [I-].Fc1ccc([Zn+])c(Cl)c1 | 100ml | 532652663](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696320.jpg-250.jpg)
eMolecules 497923-83-8 | 2-Chloro-4-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | MFCD02260160 | 321.820 | C6H3ClFIZn | 0.000 | [I-].Fc1ccc([Zn+])c(Cl)c1 | 100ml | 532652663
2-Chloro-4-fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 497923-83-8 | MFCD02260160 | 321.820 | C6H3ClFIZn | 0.000 | [I-].Fc1ccc([Zn+])c(Cl)c1 | 100ml | 532652663
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![eMolecules 108894-99-1 | (2,4,6-Triisopropylphenyl)magnesium bromide, 0.5 M in THF | Synthonix307.558 | C15H23BrMg | 0.000 | [Br-].CC(C)c1cc(C(C)C)c([Mg+])c(c1)C(C)C | 100ml | 812584993](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502694400.jpg-250.jpg)
eMolecules 108894-99-1 | (2,4,6-Triisopropylphenyl)magnesium bromide, 0.5 M in THF | Synthonix307.558 | C15H23BrMg | 0.000 | [Br-].CC(C)c1cc(C(C)C)c([Mg+])c(c1)C(C)C | 100ml | 812584993
(2,4,6-Triisopropylphenyl)magnesium bromide, 0.5 M in THF | Synthonix | 108894-99-1307.558 | C15H23BrMg | 0.000 | [Br-].CC(C)c1cc(C(C)C)c([Mg+])c(c1)C(C)C | 100ml | 812584993
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![eMolecules 849619-05-2 | (3-(trifluoromethyl)pyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix291.380 | C6H3BrF3NZn | 0.000 | [Br-].FC(F)(F)c1cccnc1[Zn+] | 100ml | 532652977](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696020.jpg-250.jpg)
eMolecules 849619-05-2 | (3-(trifluoromethyl)pyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix291.380 | C6H3BrF3NZn | 0.000 | [Br-].FC(F)(F)c1cccnc1[Zn+] | 100ml | 532652977
(3-(trifluoromethyl)pyridin-2-yl)zinc bromide, 0.25 M in THF | Synthonix | 849619-05-2291.380 | C6H3BrF3NZn | 0.000 | [Br-].FC(F)(F)c1cccnc1[Zn+] | 100ml | 532652977
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Medchemexpress LLC Vardenafil hydrochloride trihydrate | 330808-88-3 | 99.7% | 1 ML
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Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. It shows inhibitory effects towards PDE1 and PDE6 with IC50s of 180 nM and 11 nM, respectively, while its IC50s are >1000 nM for PDE3 and PDE4. This compound competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis, thereby increasing cGMP levels.
- Selective and orally active inhibitor of phosphodiesterase-5 (PDE5).
- Competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis.
- Increases cGMP levels.
- Can be used for research related to erectile dysfunction, hepatitis, and diabetes.
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(CCCC)c1cncc(OC)n1 | 5g | 525920431](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696718.jpg-250.jpg)
eMolecules 1105511-66-7 | 2-Methoxy-6-(tributylstannyl)pyrazine | Synthonix - Stock | MFCD08275735 | 399.166 | C17H32N2OSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cncc(OC)n1 | 5g | 525920431
2-Methoxy-6-(tributylstannyl)pyrazine | Synthonix - Stock | 1105511-66-7 | MFCD08275735 | 399.166 | C17H32N2OSn | 97.000 | CCCC[Sn](CCCC)(CCCC)c1cncc(OC)n1 | 5g | 525920431
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![eMolecules 674346-88-4 | 4-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix287.380 | C6H4FIZn | 0.000 | [I-].Fc1ccc([Zn+])cc1 | 100ml | 532652850](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502696141.jpg-250.jpg)
eMolecules 674346-88-4 | 4-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix287.380 | C6H4FIZn | 0.000 | [I-].Fc1ccc([Zn+])cc1 | 100ml | 532652850
4-Fluorophenylzinc iodide, 0.50 M in THF | Synthonix | 674346-88-4287.380 | C6H4FIZn | 0.000 | [I-].Fc1ccc([Zn+])cc1 | 100ml | 532652850
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