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Filtered Search Results
Medchemexpress LLC Bi-1347 | 2163056-91-3 | ≥98.0% | 1 ML
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Bi-1347 is a potent, selective small-molecule inhibitor of cyclin-dependent kinase 8 (CDK8), reported IC50 ≈ 1-1.1 nM. It has demonstrated antitumoral activity in preclinical models and is used as a research tool to probe CDK8/19 biology. Supplied as a 10 mM solution in DMSO for in vitro studies; research use only.
- Potent CDK8 inhibitor (IC50 ≈ 1-1.1 nM)
- Shows antitumoral activity in preclinical models
- Also active against CDK19 with high selectivity
- Provided as 10 mM solution in DMSO for in vitro experiments
- Intended for research use only; not for human therapeutic use
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(CCCC)c1ncncc1Br | 250mg | 525910903](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446253.PNG-250.jpg)
eMolecules 1416437-21-2 | 5-Bromo-4-(tributylstannyl)pyrimidine | Synthonix - Stock | MFCD16170450 | 448.036 | C16H29BrN2Sn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1ncncc1Br | 250mg | 525910903
5-Bromo-4-(tributylstannyl)pyrimidine | Synthonix - Stock | 1416437-21-2 | MFCD16170450 | 448.036 | C16H29BrN2Sn | 94.000 | CCCC[Sn](CCCC)(CCCC)c1ncncc1Br | 250mg | 525910903
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Medchemexpress LLC Bi-3406 | 2230836-55-0 | MFCD32197204 | 100.0% | 462.46 g/mol | C23H25F3N4O3 | 10MM 1ML
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BI-3406 is a potent, selective, and orally bioavailable small-molecule inhibitor of the SOS1-KRAS protein-protein interaction. It is used as a research tool to reduce GTP-loaded RAS and to probe KRAS-dependent signaling in cellular and biochemical assays.
- Potent SOS1-KRAS interaction inhibitor (IC50 ≈ 5-6 nM).
- High selectivity for SOS1-mediated KRAS activation.
- Reduces formation of GTP-loaded RAS in cellular models.
- Available as a 10 mM stock solution in DMSO for in vitro use.
- High purity suitable for research assays (supplier-reported ≈99.95%).
- Molecular weight 462.46 g/mol and formula C23H25F3N4O3.
- CAS number 2230836-55-0 for precise identification.
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Medchemexpress LLC Ganfeborole hydrochloride | 2131798-13-3 | MFCD31657361 | 100.0% | 293.94 | C10H14BCl2NO4 | 1 MG
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Ganfeborole hydrochloride is a small-molecule antitubercular agent that inhibits Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS). Supplied as an off-white to light-yellow solid, it is intended for research use in biochemical and cellular assays; reported IC50 against Mtb LeuRS is 0.2 μM. Store sealed and away from moisture; in solvent, store at -80°C for long-term stability.
- LeuRS inhibitor with reported IC50 0.2 μM.
- High purity suitable for biochemical assays.
- Off-white to light-yellow solid form, convenient for handling.
- Available in multiple small-scale quantities for research workflows.
- Storage guidance provided for solid and solution stability.
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Medchemexpress LLC Elimusertib hydrochloride | 00-00-0 | MFCD31561442 | 99.9% | 411.89 g/mol | C20H22ClN7O | 1 ML
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Elimusertib hydrochloride is a selective ATR kinase inhibitor supplied for research use. It is available as a ready-to-use 10 mM solution in DMSO and as solid aliquots, commonly used in preclinical studies of DNA damage response and antitumor activity. Molecular formula: C20H22ClN7O; molecular weight: 411.89 g/mol.
- Selective ATR kinase inhibitor for DNA damage response research.
- Provided as a 10 mM solution in DMSO for ready-to-use assays.
- Also available in solid form across multiple milligram pack sizes for assay development.
- High purity (≈99.9%) suitable for biochemical and cellular assays.
- Stable when stored sealed, protected from moisture, at recommended temperatures.
- Manufacturer-provided data sheet and SDS available for handling and safety information.
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eMolecules 569-42-6 | NAPHTHALENE-1,8-DIOL | AstaTech | MFCD00042701 | 160.172 | C10H8O2 | 95.000 | Oc1cccc2cccc(O)c12 | 1g | 233625920
NAPHTHALENE-1,8-DIOL | AstaTech | 569-42-6 | MFCD00042701 | 160.172 | C10H8O2 | 95.000 | Oc1cccc2cccc(O)c12 | 1g | 233625920
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Medchemexpress LLC BI-1808 1mg | 1mg
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BI-1808 is a human IgG1 monoclonal antibody that targets TNFR2by blocking interaction of TNFR2 with ligand TNF- confers Fc R-dependent depletion of Treg and mediates expansion of intratumoral CD8 T cells[1]
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Medchemexpress LLC Siglec-10 Human Bi 50ug | 50ug
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Siglec-10 protein is thought to be a putative adhesion molecule that mediates sialic acid-dependent cell binding preferentially selecting -2 3- or -2 6-linked sialic acid Its sialic acid recognition site may be masked by cis interactions Siglec-10 Protein Human (Biotinylated R119A HEK293 His-Avi) is the recombinant human-derived Siglec-10 protein expressed by HEK293 with C-Avi C-His labeled tag
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Medchemexpress LLC (+)-camphor-10-sulfonic acid | 3144-16-9 | MFCD00064157 | 98.0% | 232.30 | C10H16O4S | 50g
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( )-Camphor-10-sulfonic acid (( )-10-Camphorsulfonic acid) is an effective pancreatic lipase (PL) inhibitor ( )-Camphor-10-sulfonic acid is promising for research of obesity[1]
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Medchemexpress LLC (+)-Camphor-10-sulfonic acid | 3144-16-9 | MFCD00064157 | 98.0% | 232.30 | C10H16O4S | 100g
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( )-Camphor-10-sulfonic acid (( )-10-Camphorsulfonic acid) is an effective pancreatic lipase (PL) inhibitor ( )-Camphor-10-sulfonic acid is promising for research of obesity[1]
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Medchemexpress LLC (+)-camphor-10-sulfonic acid | 3144-16-9 | MFCD00064157 | ≥98.0% | 232.3 g·mol⁻¹ | C10H16O4S | 250g
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( )-Camphor-10-sulfonic acid (( )-10-Camphorsulfonic acid) is an effective pancreatic lipase (PL) inhibitor ( )-Camphor-10-sulfonic acid is promising for research of obesity[1]
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Medchemexpress LLC Cysteamine (hydrochloride) | 156-57-0 | 99.3% | C2H8ClNS | 10 G
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Cysteamine (hydrochloride) is an orally active agent used for the treatment of nephropathic cystinosis and as an antioxidant. This compound is intended for research use only.
- Increases intracellular glutathione levels in cystinotic cells, restoring the altered redox state.
- Counteracts increased rates of apoptosis in cystinotic cells.
- Exhibits antioxidant properties by increasing glutathione production.
- Acts as an excellent scavenger of OH and HOCl, and reacts with H2O2.
- Increases the production of several heat shock proteins (HSP).
- Exerts a dose-dependent effect on doxorubicin-induced cancer cell death.
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Medchemexpress LLC Cinacalcet (hydrochloride) | 364782-34-3 | 100.0% | C22H23ClF3N | 100 MG
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Cinacalcet hydrochloride (AMG-073 hydrochloride) is an orally active, allosteric agonist of the calcium-sensing receptor (CaR), primarily utilized for the treatment of cardiovascular diseases. This high-purity compound is provided as a white to off-white solid, suitable for various research applications.
- Orally active, allosteric agonist of Ca receptor
- Used in cardiovascular disease treatment
- High purity of 100.0%
- Good solubility in various solvents
- Comprehensive documentation available
- For research use only
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Medchemexpress LLC ACHE-IN-38 hydrochloride | 120013-39-0 | 325.84 | 50 G
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ACHE-IN-38 hydrochloride (Standard) is the analytical standard of ACHE-IN-38 hydrochloride. This compound inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE), which helps alleviate memory deficits in patients with Alzheimer's Disease by potentiating cholinergic transmission.
- Analytical standard for research and analytical applications
- Inhibits acetylcholinesterase (AChE)
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
- Alleviates memory deficits in Alzheimer's Disease patients
- Potentiates cholinergic transmission
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Medchemexpress LLC Benzocaine (hydrochloride) | 23239-88-5 | MFCD00012999 | 99.8% | 201.65 | C9H12ClNO2 | 1mL
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Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain that acts on voltage-gated Na channels at a common receptor with an IC50 value of 0 8 mM at 30 mV Additionally Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca2 with an IC50 of 47 1 mM Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation[1][2][3]
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