Naphthalenes
Medchemexpress LLC Cevimeline hydrochloride (synonyms: AF102B hydrochloride) | 107220-28-0 | 98.7% | C10H18ClNOS | 1 ML
Cevimeline hydrochloride is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. It stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia. It can also cross the blood-brain barrier.
- Quinuclidine derivative of acetylcholine
- Selective and orally active muscarinic M1 and M3 receptor agonist
- Stimulates secretion by salivary glands
- Used as a sialogogue for xerostomia
- Can cross the blood-brain barrier
- For research use only
- Molecular weight: 235.77
- Appearance: white to off-white solid
- Soluble in H2O at concentrations ≥ 50 mg/mL
eMolecules Synthonix 2-Thiazolylzinc bromide 0.50 M in THF 50ml 596115995 T73171 173382-28-0 MFCD00671987 229.400 C3H2BrNSZn
Synthonix 2-Thiazolylzinc bromide 0.50 M in THF 50ml 596115995 T73171 173382-28-0 MFCD00671987 229.400 C3H2BrNSZn
eMolecules Synthonix 2-Thiazolylzinc bromide 0.50 M in THF 100ml 532652993 T73171 173382-28-0 MFCD00671987 229.400 C3H2BrNSZn
Synthonix 2-Thiazolylzinc bromide 0.50 M in THF 100ml 532652993 T73171 173382-28-0 MFCD00671987 229.400 C3H2BrNSZn
Apexbio Technology LLC MK-571 115104-28-4 50mg
MK-571 (CAS 115104-28-4) also known as L-660711 is a selective antagonist of the leukotriene D4 (LTD4) receptor a G protein-coupled receptor activated by cysteinyl leukotrienes involved in inflammatory responses MK-571 demonstrates high affinity for the LTD4 receptor with reported Ki values of 0 22 nM in guinea pig lung and 2 1 nM in human lung membranes It effectively antagonizes LTD4- and LTE4-induced contractions in guinea pig and human airway tissues as indicated by pA2 values ranging from 8 5 to 10 5 In vivo MK-571 reduces airway hyperresponsiveness and leukocyte infiltration in animal models of pulmonary inflammation Additionally MK-571 acts as a specific inhibitor of multidrug resistance protein 1 (MRP1) supporting its use in studies of leukotriene signaling and drug transport mechanisms
Apexbio Technology LLC MK-571 115104-28-4 10mg
MK-571 (CAS 115104-28-4) also known as L-660711 is a selective antagonist of the leukotriene D4 (LTD4) receptor a G protein-coupled receptor activated by cysteinyl leukotrienes involved in inflammatory responses MK-571 demonstrates high affinity for the LTD4 receptor with reported Ki values of 0 22 nM in guinea pig lung and 2 1 nM in human lung membranes It effectively antagonizes LTD4- and LTE4-induced contractions in guinea pig and human airway tissues as indicated by pA2 values ranging from 8 5 to 10 5 In vivo MK-571 reduces airway hyperresponsiveness and leukocyte infiltration in animal models of pulmonary inflammation Additionally MK-571 acts as a specific inhibitor of multidrug resistance protein 1 (MRP1) supporting its use in studies of leukotriene signaling and drug transport mechanisms
Apexbio Technology LLC MK-571 115104-28-4 5mg
MK-571 (CAS 115104-28-4) also known as L-660711 is a selective antagonist of the leukotriene D4 (LTD4) receptor a G protein-coupled receptor activated by cysteinyl leukotrienes involved in inflammatory responses MK-571 demonstrates high affinity for the LTD4 receptor with reported Ki values of 0 22 nM in guinea pig lung and 2 1 nM in human lung membranes It effectively antagonizes LTD4- and LTE4-induced contractions in guinea pig and human airway tissues as indicated by pA2 values ranging from 8 5 to 10 5 In vivo MK-571 reduces airway hyperresponsiveness and leukocyte infiltration in animal models of pulmonary inflammation Additionally MK-571 acts as a specific inhibitor of multidrug resistance protein 1 (MRP1) supporting its use in studies of leukotriene signaling and drug transport mechanisms