Phenanthrenes and derivatives
Chemscene ChemScene | (S)-TRIP | 250MG | CS-W020708 | 0.98 | 874948-63-7| MFCD10567009 | 752.96
ChemScene | (S)-TRIP | 250MG | CS-W020708 | 0.98 | 874948-63-7| MFCD10567009 | 752.96
Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 99.8% | 454.28 | 200 MG
Pexidartinib hydrochloride is a potent, orally active, selective, and ATP-competitive inhibitor of colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit. This compound induces cell apoptosis and demonstrates anti-cancer activity.
- Potent, orally active, selective, and ATP-competitive inhibitor.
- Targets colony stimulating factor 1 receptor (CSF1R) and c-Kit.
- Exhibits high selectivity over other related kinases.
- Induces cell apoptosis and demonstrates anti-cancer activity.
- IC50 of 10 nM for c-Kit and 20 nM for cFMS.
eMolecules 141-82-2 | Malonic acid | Key Organics/BIONET104.061 | C3H4O4 | 95.000 | OC(=O)CC(O)=O | 10mg | 564178359
Malonic acid | Key Organics/BIONET | 141-82-2104.061 | C3H4O4 | 95.000 | OC(=O)CC(O)=O | 10mg | 564178359
eMolecules 141-82-2 | Malonic acid | Oakwood Chemical104.061 | C3H4O4 | 99.000 | OC(=O)CC(O)=O | 1kg | 537678614
Malonic acid | Oakwood Chemical | 141-82-2104.061 | C3H4O4 | 99.000 | OC(=O)CC(O)=O | 1kg | 537678614
eMolecules 2230820-11-6 | AZD-7648 | TargetMol US380.412 | C18H20N8O2 | 0.000 | Cc1cc2ncnn2cc1Nc1ncc2n(C)c(=O)n(C3CCOCC3)c2n1 | 200mg | 894473472
AZD-7648 | TargetMol US | 2230820-11-6380.412 | C18H20N8O2 | 0.000 | Cc1cc2ncnn2cc1Nc1ncc2n(C)c(=O)n(C3CCOCC3)c2n1 | 200mg | 894473472
Medchemexpress LLC Sch-1473759 hydrochloride | 1094067-13-6 | MFCD18251447 | 99.2% | 463.00 g/mol | C20H27ClN8OS | 200 MG
SCH-1473759 hydrochloride is a small-molecule dual aurora kinase inhibitor used in research to probe cell-cycle regulation and kinase signaling. It potently inhibits Aurora A and Aurora B at low nanomolar concentrations and displays activity against several related kinases.
- Potent dual Aurora A and B inhibition (IC50 = 4 nM and 13 nM).
- Direct binding to Aurora kinases (Kd ≈ 20-30 nM).
- Additional kinase activity including VEGFR2, Src family, Chk1, and IRAK4.
- High purity (≈99.2%) and solid, white to yellow physical form.
- Soluble in DMSO and water with warming; reported in vivo formulation options available.
- Suitable for cell-cycle and kinase signaling research applications.
- Recommended sealed storage; in solvent long-term storage at -80°C.
Apexbio Technology LLC Sinapinic acid 530-59-6 200mg
Sinapinic acid (CAS 530-59-6) is an organic compound commonly utilized as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry where it facilitates the desorption and ionization of proteins and peptides for accurate molecular weight determination The compound s ability to absorb laser energy and promote analyte ionization underpins its effectiveness in proteomics research Additionally sinapinic acid is naturally occurring in propolis contributing to the compound s significance in natural product studies Its primary research applications center on biomolecular analysis and the characterization of protein mixtures
Chemscene ChemScene | 2-Bromotriphenylene | 10G | CS-W021630 | 0.98 | 19111-87-6| MFCD16659043 | 307.19
ChemScene | 2-Bromotriphenylene | 10G | CS-W021630 | 0.98 | 19111-87-6| MFCD16659043 | 307.19
Apexbio Technology LLC Oxaloacetic acid 328-42-7 200mg
Oxaloacetic acid (CAS 328-42-7) is a small molecule metabolic intermediate involved in multiple biosynthetic pathways including the citric acid cycle It modulates mitochondrial metabolism and has been shown to reduce intracellular reactive oxygen species (ROS) levels thereby attenuating oxidative stress in cells Due to these properties oxaloacetic acid serves as a valuable tool in the investigation of metabolic disorders and mitochondrial dysfunction in biomedical research
Medchemexpress LLC Gabapentin hydrochloride | 60142-95-2 | >98.0% | C9H18ClNO2 | 200 MG
Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. It functions by inhibiting neuronal Ca2+ influx and reducing neurotransmitter release. This compound, which is a GABA analog, can be used to relieve neuropathic pain.
- It is a potent calcium channel blocker.
- It is orally active.
- Inhibits neuronal calcium influx.
- Reduces neurotransmitter release.
- It is a GABA analog.
- Can be used to relieve neuropathic pain.
Medchemexpress LLC Ivabradine hydrochloride | 148849-67-6 | 99.71% | 200 MG
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). It reduces heart rate in a dose-dependent manner without affecting blood pressure.
- Potent and orally active HCN channel blocker.
- Inhibits cardiac pacemaker current (If).
- Reduces heart rate dose-dependently without modifying blood pressure.
- Exhibits anticonvulsant, anti-ischaemic, and anti-anginal activity.
- Attenuates PTZ- and PICRO-induced seizures.
- Exhibits antioxidant effects in brain areas.
- Reduces cleaved caspase-3 expression.
eMolecules 141-82-2 | Malonic acid | Oakwood Chemical104.061 | C3H4O4 | 99.000 | OC(=O)CC(O)=O | 5g | 537678610
Malonic acid | Oakwood Chemical | 141-82-2104.061 | C3H4O4 | 99.000 | OC(=O)CC(O)=O | 5g | 537678610
Medchemexpress LLC Alvespimycin (hydrochloride) | 467214-21-7 | 98.8% | 653.21 | 200 MG
Alvespimycin hydrochloride is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM. It inhibits the growth of human cancer cell lines SKBR3 and SKOV3, which overexpress Hsp90 client protein Her2, leading to down-regulation of Her2 and induction of Hsp70. It also induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells.
- Potent inhibitor of Hsp90
- Binds to Hsp90 with an EC50 of 62 ± 29 nM
- Inhibits the growth of human cancer cell lines SKBR3 and SKOV3
- Causes down-regulation of Her2
- Induces Hsp70
- Induces dose-dependent apoptosis in chronic lymphocytic leukemia (CLL) cells
- Significant reduction in tumor size in animal models
Medchemexpress LLC Cetirizine (dihydrochloride) | 83881-52-1 | 99.6% | 461.81 | 200 MG
Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. It marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
- Second-generation antihistamine
- Carboxylated metabolite of hydroxyzine
- Specific, orally active, and long-acting histamine H1-receptor antagonist
- Marks antiallergic properties
- Inhibits eosinophil chemotaxis during the allergic response