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Medchemexpress, HY-15568A 5mg A-317491 (sodium salt hydrate) CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-B1897A 1g Menadione bisulfite (sodium) CAS:130-37-0 Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A-317491 (CAS 475205-49-3) is a selective high-affinity antagonist targeting the P2X3 and heteromeric P2X2/3 receptors ligand-gated ion channels responsive to ATP primarily located on sensory neurons involved in pain signaling It demonstrates potent inhibition with reported Ki values of 9 nM (P2X2/3) and 22 nM (P2X3) In rat dorsal root ganglion neurons A-317491 suppresses receptor-mediated currents (IC50 15 nM) in a dose-dependent manner In animal models intrathecal or peripheral administration attenuates hyperalgesia associated with inflammation and neuropathic pain underscoring its utility in pain research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More