Unsubstituted Phenols
Medchemexpress LLC Cl2a-sn-38 | 1279680-68-0 | 1480.61 | C73H97N11O22 | 50 MG
CL2A-SN-38 is a drug-linker conjugate composed of the DNA topoisomerase I inhibitor SN-38 linked via a hydrolyzable CL2A linker, intended for antibody-drug conjugate (ADC) research and development. It releases active SN-38 within tumor cells and the tumor microenvironment, producing bystander antitumor effects.
- Drug-linker conjugate designed for ADC development.
- Releases SN-38 within tumor cells and tumor microenvironment.
- Camptothecin-class topoisomerase I inhibitor mechanism.
- Molecular formula C73H97N11O22; molecular weight 1480.61.
- Soluble in DMSO (100 mg/mL) and in documented in vivo formulations.
- Store at -20°C under nitrogen; in solution -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences L-(-)-Norepinephrine (+)-bitartrate salt monohydrate meets USP testing specifications | 108341-18-0 | MFCD00150449 | 5G
L-(-)-Norepinephrine (+)-bitartrate salt monohydrate meets USP testing specifications | Mol Wt: 337.28 | 108341-18-0 | MFCD00150449 | 5G
Medchemexpress LLC Cl2-SN-38 | 1036969-20-6 | 99.2% | 1627.79 | C82H106N12O23 | 5 MG
CL2-SN-38 is a cleavable linker-based SN-38 conjugate intended as a payload for antibody-drug conjugate (ADC) research. It enables targeted delivery of the topoisomerase I inhibitor SN-38 by conjugation to antibodies such as the anti-Trop-2 humanized antibody hRS7, and is suitable for in vitro and in vivo cancer research, ADC development, and linker stability studies.
- Cleavable linker enabling controlled payload release.
- Contains the topoisomerase I inhibitor SN-38 as the cytotoxic payload.
- Designed for conjugation to antibodies for ADC development.
- High purity (>99%) suitable for preclinical research.
- Available in multiple small-scale quantities for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences Phenol BioXtra, 99.5 (GC), 108-95-2, MFCD00002143
Phenol BioXtra, 99.5 (GC)
Medchemexpress LLC Darbufelone mesylate | 139340-56-0 | MFCD00906463 | 99.7% | 428.57 | C19H28N2O5S2 | 50 MG
Darbufelone mesylate is a research-grade small molecule that inhibits cellular production of prostaglandin F2α and leukotriene B4, with preferential activity against PGHS-2. It is supplied as a solid, high-purity salt suitable for in vitro pharmacology and assay development.
- Dual inhibitor of PGF2α and LTB4 production.
- Potent PGHS-2 inhibition (IC50 = 0.19 μM).
- High-purity solid suitable for research applications.
- Available in small pack sizes for assay development.
- Datasheet, COA, and SDS available for quality and safety information.
Medchemexpress LLC Combretastatin A-1 | 109971-63-3 | 97.0% | 5 MG
Combretastatin A-1 is a microtubule polymerization inhibitor supplied as a high-purity research standard for in vitro studies. It binds the colchicine-binding site on tubulin and is commonly used to investigate microtubule dynamics and anticancer mechanisms.
- Purity 97.0%.
- Molecular weight 332.35 g/mol.
- Chemical formula C18H20O6.
- Supplied as a 5 mg solid.
- Suitable for research and analytical applications.
- Documentation available: datasheet, certificate of analysis, SDS, and RP-HPLC report.
Medchemexpress LLC HY-15492 5mg Medchemexpress, AG-13958 CAS:319460-94-1 Purity:>98%
Medchemexpress, HY-15492 5mg AG-13958 CAS:319460-94-1 AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC HY-N2435 5mg Medchemexpress, [8]-Shogaol CAS:36700-45-5 Purity:>98%](https://assets.fishersci.com/TFS-Assets/CCG/product-images/HY-N2435.jpg-250.jpg)
Medchemexpress LLC HY-N2435 5mg Medchemexpress, [8]-Shogaol CAS:36700-45-5 Purity:>98%
Medchemexpress, HY-N2435 5mg [8]-Shogaol CAS:36700-45-5 [8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5 μM) and inhibits COX-2 (IC50=17.5 μM). [8]-Shogaol induces apoptosis in human leukemia cells[3][4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Mirin | 299953-00-7 | MFCD05885480 | 99.2% | 220.25 | C10H8N2O2S | 50 MG
(E/Z)-Mirin is a research-grade small-molecule inhibitor of the Mre11-Rad50-Nbs1 (MRN) complex used to study DNA double-strand break signaling and ATM/ATR activation. It is supplied as a solid and as DMSO solutions, with molecular formula C10H8N2O2S, molecular weight 220.25 g/mol, CAS 299953-00-7, and reported purity ≈99.2%.
- Inhibits MRN-dependent ATM activation for DNA damage research.
- Molecular formula C10H8N2O2S; molecular weight 220.25 g/mol.
- High purity (~99.2%) appropriate for in vitro assays.
- Available as a 50 MG solid and as 10 mM solutions in DMSO.
- Useful for biochemical and cell-based studies of DNA repair pathways.
Medchemexpress LLC (+)-Tyrphostin B44 | 133550-37-5 | MFCD00209855 | 97.0% | 308.33 | C18H16N2O3 | 10 MG
(+)-Tyrphostin B44 is a small-molecule epidermal growth factor receptor (EGFR) inhibitor used in laboratory research to probe EGFR signaling and assess antitumor activity. It is supplied as a solid or as a DMSO solution and is intended for research use only.
- EGFR inhibitor for preclinical research.
- Used to study EGFR signaling and antitumor activity.
- Available as a solid or 10 mM solution in DMSO.
- Reported purity 97.0%.
- Molecular weight 308.33 g/mol.
- CAS number 133550-37-5.
- Soluble in DMSO; handle according to standard laboratory safety practices.
Medchemexpress LLC L-690330 hydrate | 2930564-26-2 | 98.0% | 316.14 g/mol | C8H14O9P2 | 5 MG
L-690330 hydrate is a research-grade small-molecule inhibitor of inositol monophosphatase (IMPase), supplied for biochemical and cell-based studies to probe IMPase activity and downstream signaling. The compound is provided as solids and ready-to-use DMSO solutions for immediate use in assays.
- Competitive inhibitor of inositol monophosphatase with low micromolar Ki values.
- High purity (≥98.0%) appropriate for research applications.
- Available as small solid quantities and pre-made DMSO solution for convenience.
- Molecular weight 316.14 g/mol; formula C8H14O9P2.
- Demonstrated to induce P-AMPK and autophagy in cell-based assays.
- Supporting documents (datasheet, COA, SDS) available.
Medchemexpress LLC HY-113972 5mg Medchemexpress, Methyl mycophenolate CAS:31858-66-9 Purity:>98%
Medchemexpress, HY-113972 5mg Methyl mycophenolate CAS:31858-66-9 Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Hoipin-8 | 2519537-70-1 | 98.9% | 100 MG
HOIPIN-8 is a small-molecule inhibitor of the linear ubiquitin chain assembly complex (LUBAC) that selectively inhibits HOIP and suppresses NF-κB signaling; reported IC50 ≈ 11 nM. Supplied as an off-white to light yellow solid sodium salt for in vitro research.
- Potent LUBAC (HOIP) inhibitor with reported IC50 ≈ 11 nM.
- Sodium salt; molecular weight 456.38 g/mol; formula C23H15F2N4NaO3.
- High purity (98.9%) solid suitable for biochemical and cell-based studies.
- Soluble in DMSO at approximately 50 mg/mL; ultrasonic assistance recommended.
- Store sealed, away from moisture and light; in solvent: -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences Phenol solution BioReagent, Saturated with 0.1 M citrate buffer, pHÂ 4.3 +/- 0.2, for molecular biology | 108-95-2 | MFCD00002143 | 100ML
Phenol solution BioReagent, Saturated with 0.1 M citrate buffer, pHÂ 4.3 +/- 0.2, for molecular biology | Mol Wt: 94.11 | 108-95-2 | MFCD00002143 | 100ML
Medchemexpress LLC Peldesine dihydrochloride | 2772702-10-8 | MFCD32878297 | 99.3% | 314.17 g/mol | C12H13Cl2N5O | 10 MG
Peldesine dihydrochloride is the dihydrochloride salt of a potent purine nucleoside phosphorylase (PNP) inhibitor used in preclinical biochemical and pharmacological research. It exhibits low-nanomolar PNP inhibition across species and suppresses T-cell proliferation, supporting studies in T-cell lymphoma, psoriasis, and HIV-related immunology.
- Potent PNP inhibition with low-nanomolar IC50s for human, rat, and mouse.
- Inhibits T-cell proliferation (IC50 ~800 nM), useful for immunology studies.
- High purity (~99.3%) suitable for research applications.
- Molecular weight 314.17 g/mol and solid, white to off-white appearance.
- Available in small research pack sizes and as DMSO solution formats for assays.