Saturated hydrocarbons
Medchemexpress LLC Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, (t-4)-tetrathioxomolybdate(2-) (2:1) | 649749-10-0 | 98.0% | 432.56 | 100 MG
ATN-224 is an orally active Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor that inhibits SOD1 activity in endothelial cells in a dose-dependent manner with an IC50 of 17.5 nM.
- Specific and high affinity for copper ions.
- Inhibits the proliferation of HUVEC (IC50=1.4±0.3 μM).
- Inhibits the activity of purified bovine SOD1 with an IC50 of 0.33±0.03 μM.
- SOD1 inhibition is time-dependent, reaching maximal inhibition by depleting copper.
- Inhibits FGF-2-induced ERK1/2 phosphorylation.
- Orally-available inorganic small molecule that inhibits Cu/Zn-SOD1 in endothelial and tumor cells.
- Significantly inhibits angiogenesis in the Matrigel plug model in mice.
- Angiogenesis inhibition occurs independently of copper depletion.
Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | 100.0% | 112.13 | 10 MM 1 ML
2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids.
- Key intermediate for total synthesis of steroids.
- High purity (99.96%).
- Detailed solubility data for in vitro and in vivo applications.
- Comprehensive documentation including Data Sheet, SDS, and COA.
- Specific storage guidance for optimal stability.
TARGETMOL CHEMICALS INC ATN-224 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ATN-224 (Bis(choline)tetrathiomolybdate) inhibits SOD1 activity in endothelial cells an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor. purity: 99%
Medchemexpress LLC 6-(4-(7-(tert-butyl)-5-(4-chloro-3-fluorophenyl)...piperazin-1-yl) nicotinic acid | 2014368-93-3 | MFCD18251438 | 99.4% | 565.04 | C30H30ClFN4O4 | 10 MG
I-287 is an orally active, selective protease-activated receptor 2 (PAR2) inhibitor used in research to modulate Gαq and Gα12/13-mediated signaling. It is supplied as a high-purity small-molecule compound characterized for pharmacology studies in cellular and animal models.
- Selective PAR2 inhibitor.
- Orally active small molecule.
- Acts as a negative allosteric regulator of Gαq and Gα12/13.
- Characterized for modulation of downstream signaling pathways.
- High purity (~99.4%) suitable for research applications.
- Available in research-scale quantities, such as 10 mg.
Medchemexpress LLC Stearic anhydride | 638-08-4 | MFCD00009004 | 99.2% | 550.94 | C36H70O3 | 5 G
Stearic anhydride is an organic anhydride used as a biochemical reagent in life-science research. Supplied as a white to off-white solid, it is used as a synthetic intermediate and reagent in biochemical assays and organic synthesis. Intended for research use only; not for human or clinical use.
- White to off-white solid appearance.
- High purity (99.24%).
- Molecular formula C36H70O3; molecular weight 550.94 g·mol-1.
- CAS number 638-08-4.
- Available in small laboratory pack sizes (5 g, 10 g, 50 g).
- Store at room temperature; in solution: -80 °C (2 years), -20 °C (1 year).
- For research use only; not for sale to patients.
Medchemexpress LLC Cycloheptane-1,3-dione | 1194-18-9 | 126.16 | 1 ML
Cycloheptane-1,3-dione (Compound 1A) is an intermediate that can be used to synthesize Compound 1-1, which exhibits anticancer activity against colon cancer.
- Molecular weight: 126.16
- Formula: C7H10O2
- Appearance: Liquid
- Color: Colorless to light yellow
- Density: 1.1 g/cm3
- Purity: 99.73%
- Solubility in DMSO: ≥ 100 mg/mL (792.64 mM)
- Product format: 10 mM in 1 mL of DMSO
- Shipping: Room temperature in continental US
- Storage (pure form): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month