Acrylic acids and derivatives
Medchemexpress LLC Resatorvid (TAK-242) | 243984-11-4 | 99.95% | 361.82 | 500 MG
Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. It inhibits NO, TNF-α, and IL-6 production with IC50s of 1.8 nM, 1.9 nM, and 1.3 nM, respectively. This compound downregulates the expression of TLR4 downstream signaling molecules MyD88 and TRIF, inhibits autophagy, and plays a pivotal role in various inflammatory diseases.
- Selectively inhibits toll-like receptor 4 (TLR4).
- Inhibits nitric oxide (NO), TNF-α, and IL-6 production.
- Downregulates the expression of TLR4 downstream signaling molecules MyD88 and TRIF.
- Inhibits autophagy.
- Plays a pivotal role in various inflammatory diseases.
- Suppresses production from LPS-stimulated human peripheral blood mononuclear cells (PBMCs).
- Reverses LPS-induced body weight loss and muscle loss in mice models.
Medchemexpress LLC HY-11109 10mg Medchemexpress, Resatorvid CAS:243984-11-4 Purity:>98%
Medchemexpress, HY-11109 10mg Resatorvid CAS:243984-11-4 Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-R and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-11109 100mg , TAK-242 Resatorvid CAS:243984-11-4 Purity:98%
Medchemexpress, HY-11109 100mg TAK-242 Resatorvid CAS:243984-11-4 Formula:C15H17ClFNO4S TLR4 Purity:98% TAK-242 is a potent TLR4 signaling inhibitor, selectively inhibits the TLR4-mediated production of cytokines and NO. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Ethyl (6R)-6-[N-(2-Chloro-4-Fluorophenyl)Sulfamoyl]Cyclohex-1-Ene-1-Carboxylate | CAS No: 243984-11-4 | 5mg
Ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate | Purity: ≥98% | Mol Wt: 359.8 | CAS No: 243984-11-4 | 5mg