Cyclopropanecarboxylic acids and derivatives
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Medchemexpress LLC VH032-cyclopropane-F | 2306193-99-5 | MFCD32201089 | >95.0% | 532.63 | C26H33FN4O5S | 10MM 1ML
VH032-cyclopropane-F is a VHL E3 ligase ligand used as a building block for PROTAC design and for ligand-E3 ligase binding studies. It is supplied as a 10 mM solution in DMSO (1 mL) and as a solid powder, enabling direct use in assay development or conjugation chemistry.
- Provided as 10 mM solution in DMSO (1 mL) and as powder.
- Molecular weight 532.63.
- Chemical formula C26H33FN4O5S.
- Purity ≥95%.
- Storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- Intended for use in PROTAC construction and E3 ligase binding studies.
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Medchemexpress LLC Vh032-cyclopropane-F | 2306193-99-5 | MFCD32201089 | ≥95.0% | 532.63 | C26H33FN4O5S | 10MG
VH032-cyclopropane-F is a VH032-based von Hippel-Lindau (VHL) ligand used as an E3 ligase recruiter in PROTAC design and synthesis. The compound contains a functionalized cyclopropane terminus that facilitates conjugation to target ligands via linkers, enabling construction of bifunctional degraders and in vitro evaluation of VHL-mediated activity.
- Used as an E3 ligase (VHL) ligand for PROTAC design and synthesis.
- Molecular formula C26H33FN4O5S; molecular weight 532.63.
- CAS number 2306193-99-5 for compound identification.
- Soluble in DMSO at 100 mg/mL (requires ultrasonic) and formulatable for in vivo at ≥2.5 mg/mL in common vehicle systems.
- Storage: powder at -20°C; in solvent at -80°C (6 months) or -20°C (1 month).
- Purity typically ≥95% (supplier dependent).
- Supplied in small research quantities such as 10 mg vials for synthetic applications.