Organic nitric acids and derivatives
Isosorbide mononitrate, 98+%
CAS: 16051-77-7 Molecular Formula: C6H9NO6 Molecular Weight (g/mol): 191.139 MDL Number: MFCD00143462 InChI Key: YWXYYJSYQOXTPL-SLPGGIOYSA-N Synonym: isosorbide mononitrate,isosorbide 5-mononitrate,monosorbitrate,imdur,elantan,monoket,mononit,corangin,ismn,isosorbide 5-nitrate PubChem CID: 27661 ChEBI: CHEBI:6062 IUPAC Name: [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate SMILES: C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O
Amyl Nitrate 98.0+%, TCI America™
CAS: 1002-16-0 Molecular Formula: C5H11NO3 Molecular Weight (g/mol): 133.15 MDL Number: MFCD00059177 InChI Key: HSNWZBCBUUSSQD-UHFFFAOYSA-N Synonym: Pentyl Nitrate PubChem CID: 61250 IUPAC Name: pentyl nitrate SMILES: CCCCCO[N+]([O-])=O
Isoamyl Nitrate 98.0+%, TCI America™
CAS: 543-87-3 Molecular Formula: C5H11NO3 Molecular Weight (g/mol): 133.147 MDL Number: MFCD00007042 InChI Key: NTHGIYFSMNNHSC-UHFFFAOYSA-N Synonym: Isopentyl Nitrate, 3-Methylbutyl Nitrate PubChem CID: 10985 IUPAC Name: 3-methylbutyl nitrate SMILES: CC(C)CCO[N+](=O)[O-]
Nicorandil, 98+%
CAS: 65141-46-0 Molecular Formula: C8H9N3O4 Molecular Weight (g/mol): 211.18 MDL Number: MFCD00186520 InChI Key: LBHIOVVIQHSOQN-UHFFFAOYSA-N Synonym: nicorandil,ikorel,2-nicotinamidoethyl nitrate,adancor,dancor,nicorandilum,sigmart,2-pyridine-3-carbonylamino ethyl nitrate,n-2-hydroxyethyl nicotinamide nitrate,nicorandilum inn-latin PubChem CID: 47528 ChEBI: CHEBI:31905 IUPAC Name: 2-[(pyridin-3-yl)formamido]ethyl nitrate SMILES: [O-][N+](=O)OCCNC(=O)C1=CC=CN=C1
Nicorandil 98.0+%, TCI America™
CAS: 65141-46-0 Molecular Formula: C8H9N3O4 Molecular Weight (g/mol): 211.18 MDL Number: MFCD00186520 InChI Key: LBHIOVVIQHSOQN-UHFFFAOYSA-N Synonym: nicorandil,ikorel,2-nicotinamidoethyl nitrate,adancor,dancor,nicorandilum,sigmart,2-pyridine-3-carbonylamino ethyl nitrate,n-2-hydroxyethyl nicotinamide nitrate,nicorandilum inn-latin PubChem CID: 47528 ChEBI: CHEBI:31905 IUPAC Name: 2-[(pyridin-3-yl)formamido]ethyl nitrate SMILES: [O-][N+](=O)OCCNC(=O)C1=CC=CN=C1
Medchemexpress LLC Isosorbide | 652-67-5 | 98.8% | 25 G
Isosorbide is an orally active vasodilating agent. It is researched for heart failure and angina (chest pain) and also acts as an oral hyperosmotic diuretic. It is suitable for laboratory research applications.
- Acts as an orally active vasodilating agent
- Can be used for the research of heart failure and angina
- Functions as an oral hyperosmotic diuretic
- Inhibits ADP-induced platelet aggregation
- Inhibits arachidonic acid-induced platelet aggregation
- Increases urine volume
- Reduces urinary concentrations of gallium and calcium
- Contributes to fewer renal precipitates and histopathologic changes
Selleck Chemical LLC Nicorandil S1971-50mg
Nicorandil (SG-75) is a potassium channel activator and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP)
Apexbio Technology LLC Nicorandil 65141-46-0 10mM (in 1mL DMSO)
Nicorandil (CAS 65141-46-0) is a small molecule that acts as a potassium channel opener and an activator of guanylate cyclase By facilitating potassium efflux nicorandil induces membrane hyperpolarization in vascular smooth muscle cells leading to vasodilation Additionally it enhances intracellular cyclic GMP (cGMP) levels through direct stimulation of guanylate cyclase subsequently activating protein kinase G (PKG) The activation of PKG results in downstream phosphorylation events that inhibit contractile processes in smooth muscle Nicorandil is widely used as a tool compound in cardiovascular research particularly in studies investigating angina vasorelaxation and cellular mechanisms of vascular tone regulation
Medchemexpress LLC Nicorandil | 65141-46-0 | 98.2% | 5 G
Nicorandil is a potent potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). It is a nicotinamide ester with vasodilatory and cardioprotective effects, and it has potential uses for angina and ischemic heart diseases. This process results in relaxation of smooth muscle and coronary vasodilation.
- Potent potassium channel activator
- Targets vascular nucleoside diphosphate-dependent K+ channels
- Targets cardiac ATP-sensitive K+ channels (KATP)
- Displays vasodilatory and cardioprotective effects
- Potential use for angina and ischemic heart diseases
- Activates ATP-sensitive K+ channels composed of Kir6.2 and SUR2A or 2B
- Stimulates guanylate cyclase to increase cyclic GMP (cGMP) formation
- Appears as a white to off-white solid
- Has a melting point of 92°C
Medchemexpress LLC Nicorandil | 65141-46-0 | 98.2% | 1 G
Nicorandil is a potent potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). This nicotinamide ester exhibits vasodilatory and cardioprotective effects, making it a potential treatment for angina and ischemic heart diseases.
- Potent potassium channel activator
- Targets vascular nucleoside diphosphate-dependent K+ channels
- Targets cardiac ATP-sensitive K+ channels (KATP)
- Exhibits vasodilatory effects
- Exhibits cardioprotective effects
- Potential treatment for angina
- Potential treatment for ischemic heart diseases
- Stimulates guanylate cyclase to increase cyclic GMP (cGMP) formation
- Activates protein kinase G (PKG)
- Leads to smooth muscle relaxation and coronary vasodilation
Sigma Aldrich Fine Chemicals Biosciences Isoamyl acetate 95 fCC fG
Isoamyl acetate has been identified as one of the main volatile aroma constituents in banana fruit and jackfruit. It is also formed during the fermentation of wine.
